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Oncogene received a 2023 impact factor of 6.9 and received Journal Citation Reports rankings of 18th out of 191 in the category Genetics & Heredity, 29th out of 205 in the category Cell Biology, 32nd out of 313 in the category Biochemistry & Molecular Biology, and 43rd out of 322 journals in the category Oncology. [3]
Oncogenesis is a peer-reviewed open access medical journal covering the molecular biology of cancer. It was established in 2012 by Douglas R. Green as a sister journal to Oncogene, of which Green was then editor-in-chief. [1] New articles are published exclusively online by Springer Nature on a weekly basis. [2]
The proto-oncogene can become an oncogene by a relatively small modification of its original function. There are three basic methods of activation: A mutation within a proto-oncogene, or within a regulatory region (for example the promoter region), can cause a change in the protein structure, causing an increase in protein activity
Database Institute / Organization Alteration Types Primary Source [t 1] Processed Data [t 2] Organisms Cell lines [t 3] Public Data [t 4] Restricted Data [t 5]; The BioExpress® Oncology Suite from Ocimum Bio Solutions contains gene expression data from primary, metastatic, and benign tumor samples, and normal samples, including matched adjacent controls.
B-Raf is a 766-amino acid, regulated signal transduction serine/threonine-specific protein kinase.Broadly speaking, it is composed of three conserved domains characteristic of the Raf kinase family: conserved region 1 (CR1), a Ras-GTP-binding [11] self-regulatory domain, conserved region 2 (CR2), a serine-rich hinge region, and conserved region 3 (CR3), a catalytic protein kinase domain that ...
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Oncogenomics is a sub-field of genomics that characterizes cancer-associated genes.It focuses on genomic, epigenomic and transcript alterations in cancer. Cancer is a genetic disease caused by accumulation of DNA mutations and epigenetic alterations leading to unrestrained cell proliferation and neoplasm formation.