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William Thomas Astbury FRS (25 February 1898 – 4 June 1961) was an English physicist and molecular biologist who made pioneering X-ray diffraction studies of biological molecules. [1] His work on keratin provided the foundation for Linus Pauling 's discovery of the α-helix .
Free-electron lasers have been developed for use in X-ray diffraction and crystallography. [27] These are the brightest X-ray sources currently available; with the X-rays coming in femtosecond bursts. The intensity of the source is such that atomic resolution diffraction patterns can be resolved for crystals otherwise too small for collection.
An X-ray diffraction pattern of a crystallized enzyme. The pattern of spots (reflections) and the relative strength of each spot (intensities) can be used to determine the structure of the enzyme. The relative intensities of the reflections provides information to determine the arrangement of molecules within the crystal in atomic detail.
Portrait of William Lawrence Bragg taken when he was around 40 years old. Sir William Lawrence Bragg (31 March 1890 – 1 July 1971), known as Lawrence Bragg, was an Australian-born British physicist and X-ray crystallographer, discoverer (1912) of Bragg's law of X-ray diffraction, which is basic for the determination of crystal structure.
The first X-ray diffraction experiment was conducted in 1912 by Max von Laue, [7] while electron diffraction was first realized in 1927 in the Davisson–Germer experiment [8] and parallel work by George Paget Thomson and Alexander Reid. [9] These developed into the two main branches of crystallography, X-ray crystallography and electron ...
1905 - Charles Glover Barkla discovered the X-ray polarization effect. [45] 1908 - Bernhard Walter and Robert Wichard Pohl observed X-ray diffraction from a slit. [46] [47] 1912 - Max von Laue discovered diffraction patterns from crystals in an x-ray beam. [48]
The concept of Bragg diffraction applies equally to neutron diffraction [4] and approximately to electron diffraction. [5] In both cases the wavelengths are comparable with inter-atomic distances (~ 150 pm). Many other types of matter waves have also been shown to diffract, [6] [7] and also light from objects with a larger ordered structure ...
X-ray optics is the branch of optics dealing with X-rays, rather than visible light.It deals with focusing and other ways of manipulating the X-ray beams for research techniques such as X-ray diffraction, X-ray crystallography, X-ray fluorescence, small-angle X-ray scattering, X-ray microscopy, X-ray phase-contrast imaging, and X-ray astronomy.