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Gottron's sign is a pathognomonic cutaneous manifestation associated with dermatomyositis (DM), which is an inflammatory disorder affecting the skin and muscles. [1] The primary lesion of dermatomyositis appears as a violaceous, macular erythema with a symmetric distribution, which may progress and become poikilodermatous (atrophic with telangiectasia and pigmentary changes) and indurated (as ...
Small, irregular reddish-brown telangiectatic macules covering a tan to brown backdrop are the usual appearance of TMEP lesions. [3] The diameter of a single lesion is often between 2 and 4 mm. [4] During a diascopy, the telangiectatic lesions typically blanch.
Maculopapular rash on the abdomen after 3 days of measles infection A maculopapular rash is a type of rash characterized by a flat, red area on the skin that is covered with small confluent bumps. It may only appear red in lighter-skinned people.
Erythema annulare centrifugum (EAC), is a descriptive term for a class of skin lesion [2] presenting redness in a ring form (anulare) that spreads from a center (centrifugum). It was first described by Darier in 1916.
Confluent erythematous and edematous patches on cheeks ("slapped cheek") for 1–4 days followed by a "lacy," reticular, erythematous rash on the body. Roseola infantum (exanthem subitum) "sixth disease" HHV-6 and HHV-7: Rapid onset of erythematous, blanching macules and papules surrounded by white halos on the trunk after 3–5 days of high fever.
The diagnosis may confirm any number of conditions. The presence of a rash may aid diagnosis; associated signs and symptoms are diagnostic of certain diseases. For example, the rash in measles is an erythematous, morbilliform, maculopapular rash that begins a few days after the fever starts. It classically starts at the head, and spreads downwards.
The most common skin manifestation is a diffuse macular-papular erythematous rash, which is quite nonspecific. [40] The rash varies over time and is characteristically located on the trunk; it may further spread to involve the face, extremities, and perineum. [4]
Intravenous immunoglobulin may also improve outcomes. [1] Most people improve with treatment and in some, the condition resolves completely. [1] About one in 100,000 people receive a new diagnosis of dermatomyositis each year. [2] The condition usually occurs in those in their 40s and 50s with women being affected more often than men. [2]