Search results
Results from the WOW.Com Content Network
The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...
It is removed from the body unchanged via the lungs, and does not accumulate under normal conditions, explaining the rapid offset of around 60 seconds. [1] It is effective in managing pain during labor and delivery. [15] Nitrous oxide has been shown to be an effective and safe treatment for alcohol withdrawal. [16]
Effective dose is a dose quantity in the International Commission on Radiological Protection (ICRP) system of radiological protection. [1]It is the tissue-weighted sum of the equivalent doses in all specified tissues and organs of the human body and represents the stochastic health risk to the whole body, which is the probability of cancer induction and genetic effects, of low levels of ...
The AUC (from zero to infinity) represents the total drug exposure across time. AUC is a useful metric when trying to determine whether two formulations of the same dose (for example a capsule and a tablet) result in equal amounts of tissue or plasma exposure. Another use is in the therapeutic drug monitoring of drugs with a narrow therapeutic ...
The collective effective dose, dose quantity S, is calculated as the sum of all individual effective doses over the time period or during the operation being considered due to ionizing radiation. [ 1 ] : paragraph 159 It can be used to estimate the total health effects of a process or accidental release involving ionizing radiation to an ...
Dosage typically includes information on the number of doses, intervals between administrations, and the overall treatment period. [3] For example, a dosage might be described as "200 mg twice daily for two weeks," where 200 mg represents the individual dose, twice daily indicates the frequency, and two weeks specifies the duration of treatment.
Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. [ 1 ] When a drug has a narrow therapeutic index , titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small. [ 2 ]
CDE is defined by the United States Nuclear Regulatory Commission in Title 10, Section 20.1003, of the Code of Federal Regulations (10 CFR 20.1003), such that "The Committed dose equivalent, CDE (H T,50) is the dose to some specific organ or tissue of reference (T) that will be received from an intake of radioactive material by an individual during the 50-year period following the intake".