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Benzoyl chloride, also known as benzenecarbonyl chloride, is an organochlorine compound with the formula C 7 H 5 ClO. It is a colourless, fuming liquid with an irritating odour, and consists of a benzene ring ( C 6 H 6 ) with an acyl chloride ( −C(=O)Cl ) substituent .
It is used as an intermediate in the synthesis of benzoyl chloride, benzotrifluoride and 2,4-dihydroxybenzophenone which in turn are also intermediates in other reactions: [2] C 6 H 5 CCl 3 + resorcinol → 2,4-dihydroxybenzophenone [3] [4] C 6 H 5 CCl 3 + H 2 O → C 6 H 5 C(O)Cl + 2 HCl [5] C 6 H 5 CCl 3 + 3 KF → C 6 H 5 CF 3 + 3 KCl [6]
Benzyl chloride, or α-chlorotoluene, is an organic compound with the formula C 6 H 5 CH 2 Cl. This colorless liquid is a reactive organochlorine compound that is a ...
Chloroformates are used as reagents in organic chemistry. For example, benzyl chloroformate is used to introduce the Cbz (carboxybenzyl) protecting group and fluorenylmethyloxycarbonyl chloride is used to introduce the FMOC protecting group. Chloroformates are popular in the field of chromatography as derivatization agents.
Chlorobenzene (abbreviated PhCl) is an aryl chloride and the simplest of the chlorobenzenes, consisting of a benzene ring substituted with one chlorine atom. Its chemical formula is C 6 H 5 Cl. This colorless, flammable liquid is a common solvent and a widely used intermediate in the manufacture of other chemicals. [6]
Benzyl chloroformate, also known as benzyl chlorocarbonate or Z-chloride, is the benzyl ester of chloroformic acid. It can be also described as the chloride of the benzyloxycarbonyl (Cbz or Z) group. In its pure form it is a water-sensitive oily colorless liquid, although impure samples usually appear yellow.
Benzoyl peroxide is an over the counter, FDA-approved active ingredient used primarily for the treatment of acne, according to board-certified dermatologist Dr. Marguerite Germain. This ingredient ...
4-Chlorobenzoic acid is an organic compound with the molecular formula ClC 6 H 4 CO 2 H. It is a white solid that is soluble in some organic solvents and in aqueous base. 4-Chlorobenzoic acid is prepared by oxidation of 4-chlorotoluene .