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A corpus callosotomy (/ k ə ˈ l ɔː s (ə) t ə m iː /) is a palliative surgical procedure for the treatment of medically refractory epilepsy. [1] The procedure was first performed in 1940 by William P. van Wagenen. [2] In this procedure, the corpus callosum is cut through, in an effort to limit the spread of epileptic activity between the ...
The corpus callosum is the primary communication mechanism between the brain's two cerebral hemispheres. For example, communication across the corpus callosum allows information from both the left and right visual fields to be interpreted by the brain in a way that makes sense to comprehend the person's actual experience (visual inputs from ...
Split-brain or callosal syndrome is a type of disconnection syndrome when the corpus callosum connecting the two hemispheres of the brain is severed to some degree. It is an association of symptoms produced by disruption of, or interference with, the connection between the hemispheres of the brain.
In the early 1960s, the team of the neurosurgeon Joseph Bogen, the neuropsychologist Roger Sperry, and the "psychobiology" graduate student Michael Gazzaniga performed psychological experiments on patients who for medical treatment had undergone "split-brain surgery" which cuts the corpus callosum and thus severs the main link between the two sides of the brain known as the cerebral hemispheres.
Early studies showed evidence that there may be an interhemispheric transfer deficit among people with alexithymia; that is, the emotional information from the right hemisphere of the brain is not being properly transferred to the language regions in the left hemisphere, as can be caused by a decreased corpus callosum, often present in ...
A further example of how brain structure can influence ASD is looking at cases where the corpus callosum does not fully develop (agenesis of corpus callosum). It was found that autism is commonly diagnosed in children where the corpus callosum does not fully develop (45% of children with agenesis of the corpus callosum). [46]
As a treatment for epilepsy the corpus callosum may be severed to cut the major connection between the hemispheres in a procedure known as a corpus callosotomy. A hemispherectomy is the removal or disabling of one of the hemispheres of the brain. This is a rare procedure used in some extreme cases of seizures which are unresponsive to other ...
Agenesis of the corpus callosum (ACC) is a rare congenital disorder that is one of the most common brain malformations observed in human beings, [30] in which the corpus callosum is partially or completely absent. ACC is usually diagnosed within the first two years of life, and may manifest as a severe syndrome in infancy or childhood, as a ...