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Before this can happen, the FDA must first permit the study of the medical benefits and drawbacks of the substance, which it has not done since it was placed on Schedule I of the Controlled Substances Act in 1970. Therefore, all expenses incurred fulfilling a medical marijuana prescription will possibly be incurred as out-of-pocket. [142]
In dogs, the minimum lethal dose of THC is over 3000 mg/kg. [20] According to The Merck Index, [21] the LD 50 of THC (the dose which causes the death of 50% of individuals) is 1270 mg/kg for male rats and 730 mg/kg for female rats from oral consumption in sesame oil, and 42 mg/kg for rats from inhalation. [22]
There is significant variation in medical cannabis laws from state to state, including how it is produced and distributed, how it can be consumed, and what medical conditions it can be used for. [2] The first state to effectively legalize medical cannabis was California in 1996, when voters approved Proposition 215 by a 56–44 margin.
Over time, the marijuana gateway hypothesis has been studied more and more. In one published study, the use of marijuana was shown not a reliable gateway cause of illicit drug use. [67] However, social factors and environment influence drug use and abuse, making the gateway effects of cannabis different for those in differing social circumstances.
Using a more sensitive cutoff of 20 ng/mL (less common but still used by some labs), the most likely maximum times are 7 days and 21 days, respectively. In extraordinary circumstances of extended marijuana use, detection times of more than 30 days are possible in some individuals at the 20 ng/mL cutoff. [7]
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Cannabinoid hyperemesis syndrome (CHS) is recurrent nausea, vomiting, and cramping abdominal pain that can occur due to prolonged, high-dose cannabis use. [4] [5] Complications are related to persistent vomiting and dehydration which may lead to kidney failure and electrolyte problems. [2]
Let’s talk 5mg finasteride vs 1mg—two different doses, one powerful hair loss treatment. Finasteride is the active ingredient in Propecia®, an oral medication that’s clinically-proven to ...