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Bile acid malabsorption (BAM), known also as bile acid diarrhea, is a cause of several gut-related problems, the main one being chronic diarrhea.It has also been called bile acid-induced diarrhea, cholerheic or choleretic enteropathy, bile salt diarrhea or bile salt malabsorption.
Bile acid sequestrants are polymeric compounds that serve as ion-exchange resins. Bile acid sequestrants exchange anions such as chloride ions for bile acids. By doing so, they bind bile acids and sequester them from the enterohepatic circulation. The liver then produces more bile acids to replace those that have been lost.
These side effects often lead to low patient compliance. [ 5 ] Colesevelam can be used instead of cholestyramine in symptomatic chronic diarrhea due to bile salt malabsorption ( bile acid diarrhea ), which can be a primary condition, or secondary to Crohn's disease or the postcholecystectomy syndrome .
Bempedoic acid. Fibrates. Bile acid sequestrants. Niacin. PCSK9 inhibitors. More research is needed to find out if supplements like green tea, ginger, garlic, fiber, and red yeast rice could help ...
GLP-1 drugs used for weight loss involve all kinds of side effects—good and not-so-good—that may or may not strike the average user. ... These meds can slow the movement of bile—stuff ...
Colestipol (trade names Colestid, Cholestabyl) is a bile acid sequestrant used to lower blood cholesterol, specifically low-density lipoprotein (LDL). [1] [2] It is also used to reduce stool volume and frequency, and in the treatment of chronic diarrhea. [3]
Lighter Side. Medicare. ... But calcium may have a protective effect against colorectal cancer because it binds to bile acids and free fatty acids in the colon, which helps reduce their cancer ...
Bile acids also have hormonal actions throughout the body, particularly through the farnesoid X receptor and GPBAR1 (also known as TGR5). [7] Bile acid synthesis is the only manner in which humans or other mammals may excrete excess cholesterol, as the parent compound of all bile acids is cholesterol. [citation needed]
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