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Doxylamine and other first-generation antihistamines are the most widely used sleep medications in the world. [6] Typical side effects of doxylamine (at recommended doses) include dizziness, drowsiness, grogginess, and dry mouth, among others. [7] [4] As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor.
Sleep has been shown to have a long list of physical and mental health benefits, and now a new study suggests it could also help to “erase" bad memories. Experts comment on the findings.
The study also reports that the commonly prescribed sleep aid zolpidem — marketed under the name Ambien — may suppress those oscillations, disrupting the brain’s waste removal during sleep.
They also have an elevated metabolic rate, which does not occur in people who do not have insomnia but whose sleep is intentionally disrupted during a sleep study. Studies of brain metabolism using positron emission tomography (PET) scans indicate that people with insomnia have higher metabolic rates by night and by day.
Three subsequent 2014 systematic reviews that included the Cochrane review in their analysis concluded with similar findings: one indicated that physical exercise is effective as an adjunct treatment with antidepressant medication; [170] the other two indicated that physical exercise has marked antidepressant effects and recommended the ...
One 2019 study found that a twice-daily dose of ashwagandha led to a reduction in anxiety and improved sleep. Another study of just 50 adults found that taking ashwagandha every day for 12 weeks ...
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