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The oftentimes severe methemoglobinemia found in sodium nitrite poisoning cases results in systemic hypoxia, metabolic acidosis, and cyanosis. [50] The reported [51] signs of sodium nitrite poisoning are as follows: "Symptoms of [nitrite] poisoning can vary depending on the amount and duration of the exposure.
Cyanide is a potent cytochrome c oxidase (COX, a.k.a. Complex IV) inhibitor, causing asphyxiation of cells. As such, cyanide poisoning is a form of histotoxic hypoxia, because it interferes with the ability of cells to take or use oxygen via oxidative phosphorylation. [25]: 1475. Specifically, cyanide binds to the heme a3-CuB binuclear center ...
The nitrite ion has the chemical formula NO − 2. Nitrite (mostly sodium nitrite) is widely used throughout chemical and pharmaceutical industries. [1] The nitrite anion is a pervasive intermediate in the nitrogen cycle in nature. The name nitrite also refers to organic compounds having the –ONO group, which are esters of nitrous acid.
Sea salt is one of the most common causes of sodium poisoning. Salt poisoning is an intoxication resulting from the excessive intake of sodium (usually as sodium chloride) in either solid form or in solution (saline water, including brine, brackish water, or seawater). Salt poisoning sufficient to produce severe symptoms is rare, and lethal ...
Biological functions of nitric oxide are roles that nitric oxide plays within biology. Nitric oxide (nitrogen monoxide) is a molecule and chemical compound with chemical formula of N O . In mammals including humans, nitric oxide is a signaling molecule involved in several physiological and pathological processes. [ 1 ]
Histotoxic hypoxia (also called histoxic hypoxia) is the inability of cells to take up or use oxygen from the bloodstream, despite physiologically normal delivery of oxygen to such cells and tissues. [1] Histotoxic hypoxia results from tissue poisoning, such as that caused by cyanide (which acts by inhibiting cytochrome oxidase) and certain ...
After curing completes, the concentration of these compounds appears to degrade over time. Their presence in finished products has been tightly regulated since several food-poisoning cases in the early 20th century, [1] but consumption of large quantities of processed meats can still cause a slight elevation in gastric and oesophageal cancer ...
Nitrates and nitrites extend shelf life, [citation needed] help kill bacteria, produce a characteristic flavor and give meat a pink or red color. [17] Nitrite (NO − 2) is generally supplied by sodium nitrite or (indirectly) by potassium nitrate. Nitrite salts are most often used to accelerate curing and impart a pink colour. [18]