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Elevated or normal serum vitamin B 12 levels may also be associated with a functional vitamin deficiency. [1] Functional deficiency has been described despite high B 12 concentrations and is due to a failure of cellular uptake, intracellular processing, trafficking, or utilization. [1] However, low vitamin B 12 levels may occur other than the ...
"B12" and "Cbl" redirect here. For other uses of B12, see B12 (disambiguation). For the musical group, see Carbon Based Lifeforms. Pharmaceutical compound Vitamin B12 General skeletal formula of cobalamins Stick model of cyanocobalamin (R = CN) based on the crystal structure Clinical data Other names Vitamin B12, vitamin B-12, cobalamin AHFS / Drugs.com Monograph MedlinePlus a605007 License ...
Other symptoms of vitamin B12 deficiency include memory loss, fatigue and weakness, nerve damage causing numbness and tingling in the arms and legs, dementia, depression, and seizures.
Evidence exists linking elevated homocysteine levels with vascular dementia [10] and Alzheimer's disease. [11] [12] [13] There is also evidence that elevated homocysteine levels and low levels of vitamin B6 and B12 are risk factors for mild cognitive impairment and dementia. [14]
Just don’t exceed 1,000 micrograms of total daily folate, the NIH says, as high doses can hide or exacerbate B12 deficiency and potentially increase risks of colorectal cancer. Multivitamins (maybe)
Blood tests may show low levels of vitamin B 12, elevated levels of methylmalonic acid or homocysteine, and a routine complete blood counts may shows anemia with an elevated mean cell volume. [140] The presence of antibodies to gastric parietal cells and intrinsic factor may indicate pernicious anemia. [2]
Vitamin B12 deficiency symptoms. In addition to weakness and fatigue, a B12 deficiency may also prompt a slew of other symptoms, depending on the severity, including: pale skin.
[56] [57] Low levels of serum vitamin B 12 may be caused by other factors than B 12 deficiency, such as folate deficiency, pregnancy, oral contraceptive use, haptocorrin deficiency, and myeloma. [57] High serum levels may caused by supplementing with vitamin B 12, present of antibodies to intrinsic factor, or due to underlying condition. [56]
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