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Luteinizing hormone (LH, also known as luteinising hormone, [1] lutropin and sometimes lutrophin [2]) is a hormone produced by gonadotropic cells in the anterior pituitary gland. The production of LH is regulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus. [ 3 ]
The anterior portion of the pituitary gland produces luteinizing hormone (LH) and follicle-stimulating hormone (FSH), and the gonads produce estrogen and testosterone. In oviparous organisms (e.g. fish, reptiles, amphibians, birds), the HPG axis is commonly referred to as the hypothalamus-pituitary-gonadal-liver axis (HPGL-axis) in females ...
Gonadotropic cells (also known as gonadotropes, gonadotrophs, delta cells, or delta basophils) are endocrine cells in the anterior pituitary that produce gonadotropins.More specifically, gonadotrophs produce and secrete glycoprotein polypeptide hormones, such as the follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which are released due to the positive input of gonadotropin ...
Gonadotropins are glycoprotein hormones secreted by gonadotropic cells of the anterior pituitary of vertebrates. [1] [2] [3] This family includes the mammalian hormones follicle-stimulating hormone (FSH) and luteinizing hormone (LH), the placental/chorionic gonadotropins, human chorionic gonadotropin (hCG) and equine chorionic gonadotropin (eCG), [3] as well as at least two forms of fish ...
Gonadotropin releasing hormone (GnRH) is released by projections of the hypothalamus into the anterior pituitary gland. Gonadotrophs are stimulated to produce follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which are released into the bloodstream to act upon the ovaries. Luteinizing hormone serves to directly stimulate theca cells.
2796 14714 Ensembl ENSG00000147437 ENSMUSG00000015812 UniProt P01148 P13562 RefSeq (mRNA) NM_001083111 NM_000825 NM_008145 RefSeq (protein) NP_000816 NP_001076580 NP_032171 Location (UCSC) Chr 8: 25.42 – 25.42 Mb Chr 14: 67.98 – 67.99 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Gonadotropin-releasing hormone (GnRH) is a releasing hormone responsible for the release of ...
Progesterone is released in response to high blood levels of luteinizing hormone. It works with estrogens in establishing the menstrual cycle. The testes of the male begin to produce testosterone at puberty in response to luteinizing hormone. Testosterone promotes maturation of the male reproductive organs, development of secondary sex ...
LH is released from the pituitary gland along with FSH in response to GnRH release into the hypophyseal portal system. [4] Pulsatile GnRH release causes pulsatile LH and FSH release to occur, which modulates and maintains appropriate levels of bioavailable gonadal hormone—testosterone in males and estradiol in females—subject to the requirements of a superior feedback loop. [3]