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  2. Risankizumab - Wikipedia

    en.wikipedia.org/wiki/Risankizumab

    Risankizumab was approved by the U.S. Food and Drug Administration (FDA) for treatment of moderate-to-severe plaque psoriasis in April 2019. [13] [10] [14]The FDA approved risankizumab based on evidence primarily from five clinical trials (Trial 1/NCT02684370, Trial 2/NCT02684357, Trial 3/NCT02672852, Trial 4/ NCT02694523, and Trial 5/NCT02054481) of 1606 participants with moderate to severe ...

  3. Adalimumab - Wikipedia

    en.wikipedia.org/wiki/Adalimumab

    Adalimumab, sold under the brand name Humira and others, is a disease-modifying antirheumatic drug and monoclonal antibody used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, and uveitis.

  4. TNF inhibitor - Wikipedia

    en.wikipedia.org/wiki/TNF_inhibitor

    A TNF inhibitor is a pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response.TNF is involved in autoimmune and immune-mediated disorders such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriasis, hidradenitis suppurativa and refractory asthma, so TNF inhibitors may be used in their ...

  5. Ustekinumab - Wikipedia

    en.wikipedia.org/wiki/Ustekinumab

    Ustekinumab is used to treat psoriasis. [29] This includes psoriatic arthritis when it affects the skin. [31] [29] It is indicated for the treatment of adult and adolescent patients (12 years and older) with moderate to severe plaque psoriasis (Ps) who are candidates for phototherapy or systemic therapy, and adults with active psoriatic arthritis (PsA) alone or in combination with methotrexate.

  6. Tildrakizumab - Wikipedia

    en.wikipedia.org/wiki/Tildrakizumab

    As of March 2014, the drug was in phase III clinical trials for plaque psoriasis. The two trials enrolled nearly 2000 participants. [12] [13] In 2016, tildrakizumab became the first IL-23p19 inhibitor to demonstrate positive results in Phase-3 clinical trials for the treatment of moderate-to-severe plaque psoriasis, further validating the ...

  7. Management of Crohn's disease - Wikipedia

    en.wikipedia.org/wiki/Management_of_Crohn's_disease

    Many clinical trials have been recently completed or are ongoing for new therapies for Crohn's disease. They include the following: They include the following: Certolizumab is a PEGylated Fab fragment of a humanized anti-TNFα monoclonal antibody that was found to have efficacy over placebo in one large trial.

  8. America’s Most Admired Lawbreaker - The Huffington Post

    highline.huffingtonpost.com/miracleindustry/...

    Creating wealth by fighting pain, disease, death. One could imagine Robert Wood Johnson, who founded the company with two of his brothers in New Brunswick in 1886 looking down proudly on the Hyatt ballroom—and in dismay at the grand jury hearings, depositions and trials that told the Risperdal story. Putting Patients First

  9. Infliximab - Wikipedia

    en.wikipedia.org/wiki/Infliximab

    Infliximab, a chimeric monoclonal antibody, sold under the brand name Remicade among others, is a medication used to treat a number of autoimmune diseases.This includes Crohn's disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriasis, psoriatic arthritis, and Behçet's disease. [23]

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