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The structure of TPI facilitates the conversion between dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (GAP). The nucleophilic glutamate 165 residue of TPI deprotonates the substrate , [ 4 ] and the electrophilic histidine 95 residue donates a proton to form the enediol intermediate.
Triosephosphate isomerase deficiency is a rare autosomal recessive [2] metabolic disorder which was initially described in 1965. [3]It is a unique glycolytic enzymopathy that is characterized by chronic haemolytic anaemia, cardiomyopathy, susceptibility to infections, severe neurological dysfunction, and, in most cases, death in early childhood. [4]
21991 Ensembl ENSG00000111669 ENSMUSG00000023456 UniProt P60174 P17751 RefSeq (mRNA) NM_001258026 NM_000365 NM_001159287 NM_009415 RefSeq (protein) NP_000356 NP_001152759 NP_001244955 NP_033441 Location (UCSC) Chr 12: 6.87 – 6.87 Mb Chr 6: 124.79 – 124.79 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Triosephosphate isomerase is an enzyme that in humans is encoded by the TPI1 ...
A National Provider Identifier (NPI) is a unique 10-digit identification number issued to health care providers in the United States by the Centers for Medicare and Medicaid Services (CMS). The NPI has replaced the Unique Physician Identification Number (UPIN) as the required identifier for Medicare services, and is used by other payers ...
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Typically, 80 TPI screws are used in mirror mounts. [1] Ultra-fine adjustment screws are used in applications requiring extremely fine motion, like laser alignment and fiber coupling . Fine and ultra-fine adjustment screws are often used in photonics applications as part of purchased equipment such as mirror mounts, or built into lab-made ...
This class of status code indicates the client must take additional action to complete the request. Many of these status codes are used in URL redirection. [2]A user agent may carry out the additional action with no user interaction only if the method used in the second request is GET or HEAD.
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