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Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodium and T-type calcium channels , which leads to the suppression of neuronal hypersynchronization ...
Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...
In juvenile myoclonic epilepsy, it is a second-line therapy, reserved for when the valproates or lamotrigine do not work and when the other second-line therapy, acetazolamide, does not work. [14] The usual dose for seizure disorder is titrated from 100-125 mg/day up to a maintenance dose of 750-1,500 mg/day (maximum daily dosage is 2 g).
Questions surrounding the identity of "Celebrity B" remain after Jay-Z was recently named in a Sean "Diddy" Combs sexual assault lawsuit.. Initially, the lawsuit stated Diddy raped the minor while ...
How To Make My 2-Ingredient Jam Bars. To make one 8x8-inch pan, or 12 to 16 bars, you’ll need: 1 (1-pound) log refrigerated sugar cookie dough
Ethosuximide, sold under the brand name Zarontin among others, is a medication used to treat absence seizures. [4] It may be used by itself or with other antiseizure medications such as valproic acid. [4]
A Northern California community came together Friday night to pray for two little boys who underwent surgery and remain in critical condition after they were wounded in a shooting at a small ...
Mental health in education is the impact that mental health (including emotional, psychological, and social well-being) has on educational performance.Mental health often viewed as an adult issue, but in fact, almost half of adolescents in the United States are affected by mental disorders, and about 20% of these are categorized as “severe.” [1] Mental health issues can pose a huge problem ...