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A tetanic contraction (also called tetanized state, tetanus, or physiologic tetanus, the latter to differentiate from the disease called tetanus) is a sustained muscle contraction [2] evoked when the motor nerve that innervates a skeletal muscle emits action potentials at a very high rate.
Tetany or tetanic seizure is a medical sign consisting of the involuntary contraction of muscles, which may be caused by disorders that increase the action potential frequency of muscle cells or of the nerves that innervate them.
Local tetanus is an uncommon form of the disease, in which people have persistent contraction of muscles in the same anatomic area as the injury. The contractions may persist for many weeks before gradually subsiding. Local tetanus is generally milder; only about 1% of cases are fatal, but it may precede the onset of generalized tetanus. [1]
The rate at which the nerve impulses arrive is known as the motor unit firing rate and may vary from frequencies low enough to produce a series of single twitch contractions to frequencies high enough to produce a fused tetanic contraction. Generally, this allows a 2 to 4-fold change in force.
Depiction of smooth muscle contraction. Muscle contraction is the activation of tension-generating sites within muscle cells. [1] [2] In physiology, muscle contraction does not necessarily mean muscle shortening because muscle tension can be produced without changes in muscle length, such as when holding something heavy in the same position. [1]
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In neurobiology, a tetanic stimulation consists of a high-frequency sequence of individual stimulations of a neuron. [ citation needed ] It is associated with potentiation . High-frequency stimulation causes an increase in release called post-tetanic potentiation (Kandel 2003).