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Deamination is the removal of an amino group from a molecule. [1] Enzymes that catalyse this reaction are called deaminases. In the human body, deamination takes place primarily in the liver; however, it can also occur in the kidney. In situations of excess protein intake, deamination is used to break down amino acids for energy.
Deamidation reaction of Asn-Gly (top right) to Asp-Gly (at left) or iso(Asp)-Gly (in green at bottom right) Deamidation is a chemical reaction in which an amide functional group in the side chain of the amino acids asparagine or glutamine is removed or converted to another functional group.
One example of this is a study conducted by D. Fattori looking at the regioselectivity of the Demjanov rearrangement in one-carbon enlargements of naked sugars. It showed that when an exo methylamine underwent Demjanov nitrous acid deamination, ring enlargement was not produced.
This page will attempt to list examples in mathematics. To qualify for inclusion, an article should be about a mathematical object with a fair amount of concreteness. Usually a definition of an abstract concept, a theorem, or a proof would not be an "example" as the term should be understood here (an elegant proof of an isolated but particularly striking fact, as opposed to a proof of a ...
Oxidative deamination is a form of deamination that generates α-keto acids and other oxidized products from amine-containing compounds, and occurs primarily in the liver. [1] Oxidative deamination is stereospecific, meaning it contains different stereoisomers as reactants and products; this process is either catalyzed by L or D- amino acid ...
For example, incorporation of adenine across from 8-oxoguanine (right) during DNA replication causes a G:C base pair to be mutated to T:A. Other examples of base lesions repaired by BER include: Oxidized bases: 8-oxoguanine, 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG, FapyA) Alkylated bases: 3-methyladenine, 7-methylguanosine
The Positive predictive value (PPV) of a test is the proportion of persons who are actually positive out of all those testing positive, and can be calculated from a sample as: PPV = True positive / Tested positive. If sensitivity, specificity, and prevalence are known, PPV can be calculated using Bayes' theorem.
[9] [10] The reaction catalyzed by PAL is a spontaneous elimination reaction rather than an oxidative deamination. [ 11 ] The cofactor 3,5-dihydro-5-methyldiene-4 H -imidazol-4-one (MIO) is involved in the reaction and sits atop the positive pole of three polar helices in the active site, which helps to increase its electrophilicity . [ 12 ]