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Ceftriaxone, sold under the brand name Rocephin, is a third-generation cephalosporin antibiotic used for the treatment of a number of bacterial infections. [4] These include middle ear infections, endocarditis, meningitis, pneumonia, bone and joint infections, intra-abdominal infections, skin infections, urinary tract infections, gonorrhea, and pelvic inflammatory disease. [4]
Individuals weighing less than 150 kg are typically prescribed a ceftriaxone concentration of 500 mg, while individuals who weigh over 150 kg are typically prescribed a dose of 1 g. Although ceftriaxone is not the only cephalosporin that has been effective at treating gonorrhoeae, it is the most advantageous. [75]
Rates of reported gonorrhea have increased 111% since the historic low in 2009. During 2019–2020, the overall rate of reported gonorrhea increased 5.7%; rates increased among both males and females and in three regions of the United States (Midwest, Northeast, and South); rates of reported gonorrhea increased in 36 states and two US territories.
Gonorrhea can be prevented with the use of condoms, having sex with only one person who is uninfected, and by not having sex. [1] [3] Treatment is usually with ceftriaxone by injection and azithromycin by mouth. [4] [5] Resistance has developed to many previously used antibiotics and higher doses of ceftriaxone are occasionally required. [4] [5]
Since August 2012, the third-generation cephalosporin, ceftriaxone, is the only recommended treatment for gonorrhea in the United States (in addition to azithromycin or doxycycline for concurrent Chlamydia treatment). Cefixime is no longer recommended as a first-line treatment due to evidence of decreasing susceptibility. [30] Ceftriaxone ...
Cefodizime is a 3rd generation cephalosporin antibiotic with broad spectrum activity against aerobic gram positive and gram negative bacteria. Clinically, it has been shown to be effective against upper and lower respiratory tract infections, urinary tract infections, and gonorrhea.
These infections include otitis media, strep throat, pneumonia, urinary tract infections, gonorrhea, and Lyme disease. [5] For gonorrhea typically only one dose is required. [6] In the United States it is a second-line treatment to ceftriaxone for gonorrhea. [5] It is taken by mouth. [5] Common side effects include diarrhea, abdominal pain, and ...
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