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A deuterated drug is a small molecule medicinal product in which one or more of the hydrogen atoms in the drug molecule have been replaced by its heavier stable isotope deuterium. Because of the kinetic isotope effect , deuterium-containing drugs may have significantly lower rates of metabolism , and hence a longer half-life .
Teva Pharmaceuticals received approval from the Food and Drug Administration to market deutetrabenazine in early 2017, along with five years of orphan drug exclusivity for the treatment of chorea associated with Huntington's disease. It was the first deuterated drug to receive FDA approval. [8] [9] [10]
Drug class Serotonergic psychedelic ; Serotonin receptor agonist [ 1 ] [ 3 ] CYB004 , or CYB-004 , also known as deuterated dimethyltryptamine ( dDMT ), is a serotonergic psychedelic related to dimethyltryptamine (DMT) which is under development for the treatment of generalized anxiety disorder .
Drug class Serotonin receptor agonist ; Serotonergic psychedelic [ 1 ] CYB005 , or CYB-005 , also known as deuterated phenethylamine derivative , is a serotonin receptor agonist and serotonergic psychedelic which is under development for use at non- hallucinogenic doses in the treatment of psychiatric disorders and neuroinflammation .
A drug class is a group of medications and other compounds that share similar chemical structures, act through the same mechanism of action (i.e., binding to the same biological target), have similar modes of action, and/or are used to treat similar diseases.
Deuterated drug: class of pharmaceutical drug 1 list: Quinolone antibiotic: class of pharmaceutical drugs, subgroup of quinolones 1 list: Antiplatelet drug: class of pharmaceuticals that decrease platelet aggregation and inhibit thrombus formation 1 list: Antiprotozoal: class of pharmaceuticals used in treatment of protozoan infection 1 list ...
Twenty dangerous opioids and drugs will be banned in a new crackdown announced by the Home Office.. The ban will see 15 new dangerous synthetic opioids and five other drugs become Class A drugs ...
It is a tryptamine derivative and is a deuterated analogue of psilocybin and psilocin. [ 1 ] [ 4 ] [ 5 ] [ 2 ] The pharmacodynamic profile of CYB003, including its interactions with serotonin receptors and its effects in animals, is similar to that of psilocin. [ 2 ]