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Hexahydrocannabinol (HHC) is a hydrogenated derivative of tetrahydrocannabinol (THC). It is a naturally occurring phytocannabinoid that has rarely been identified as a trace component in Cannabis sativa, [1] [2] but can also be produced synthetically by firstly acid cyclization of cannabidiol and then hydrogenation of tetrahydrocannabinol.
9-Hydroxyhexahydrocannabinol (9-OH-HHC) is a semi-synthetic derivative of tetrahydrocannabinol. It is formed as an impurity in the synthesis of Delta-8-THC , [ 1 ] and retains activity in animal studies though with only around 1/10 the potency of Δ 9 -THC, with the 9α- and 9β- enantiomers having around the same potency.
The 11-OH-9β-HHC isomer is the structurally related methylene homologue of 11-Nor-9β-hydroxyhexahydrocannabinol also known as 9-Nor-9β-hydroxyhexahydrocannabinol. [8] [9] HU-243 is a synthetic analog of 11-OH-9β-HHC in which the natural n-pentyl side chain is replaced with a geminal-dimethylheptyl substitution.
The Safe and Drug-Free Schools and Communities Advisory Committee, authorized by the No Child Left Behind Act, was appointed by the U.S. Secretary of Education Margaret Spellings. The Committee was established to provide advice to the Secretary on Federal, state, and local programs designated to create safe and drug-free schools, and on issues ...
For example, Δ 9-THC has an EC 50 of 250 nM at CB 1 and 1157 nM at CB 2, whereas PB-22 has an EC 50 of 5.1 nM at CB 1 and 37 nM at CB 2. [8] Adverse effects observed due to synthetic cannabinoid use include acute kidney injury, cardiac toxicity, seizure, stroke, tremor, hypokalemia, and rhabdomyolysis.
Safe Schools/Healthy Students (SS/HS) is a grant program funded by the United States Department of Education, United States Department of Justice, and United States Department of Health and Human Services that helps school districts, in partnership with mental health providers, law enforcement and juvenile justice agencies, implement projects that create safe and healthy schools and communities.
However, school teachers commonly assign less homework to the students who need it most, and more homework to the students who are performing well. [9] In past centuries, homework was a cause of academic failure: when school attendance was optional, students would drop out of school entirely if they were unable to keep up with the homework ...
National School Choice Week was founded in 2011 to promote the concept of all forms of school choice: district schools, district magnet schools, charter schools, private schools, and home schooling. The event, which takes place the last week of January each year, is sponsored by the National School Choice Awareness Foundation.