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For example, if the primary tumor grade was 2 and the secondary tumor grade was 3 but some cells were found to be grade 4, the Gleason score would be 2+4=6. This is a slight change from the pre-2005 Gleason system where the second number was the secondary grade (i.e., the grade of the second-most common cell line pattern).
Of the many cancer-specific schemes, the Gleason system, [3] named after Donald Floyd Gleason, used to grade the adenocarcinoma cells in prostate cancer is the most famous. This system uses a grading score ranging from 2 to 10. Lower Gleason scores describe well-differentiated less aggressive tumors.
In contrast to the original Gleason grading system, it is now recommended that on a needle core biopsy both the most common and highest grade are added together for the Gleason score [2]. For example, if there is 60 % Gleason pattern 3, 35 % Gleason pattern 4, and 5 % Gleason pattern 5, the Gleason score would be 3 + 5 = 8.
For prostate cancer, cell morphology is graded based on the Gleason grading system. [citation needed] Of note, this system of describing tumors as "well-", "moderately-", and "poorly-" differentiated based on Gleason score of 2–4, 5–6, and 7–10, respectively, persists in SEER and other databases but is generally outdated. In recent years ...
Universities use 0–100 point grade scaling similar to the United States grading. 71 is required to pass, or roughly the equivalent of a C. Schools use the 1–5 point system, meaning if a student has a 4.5 that is the equivalent of an A− or somewhere around the 95-point range.
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In some places, .25 or .3 instead of .33 is added for a plus grade and subtracted for a minus grade. Other institutions maintain a mid-grade and award .5 for the grade. For example, an AB would receive a 3.5-grade point and a BC would receive a 2.5-grade point.
In the Czech Republic, primary and secondary schools use a 5-point grade system, with 1 as the best and 5 as the worst.They correspond to the following ratings: 1 = výborně (excellent), 2 = chvalitebně (commendable), 3 = dobře (good), 4 = dostatečně (sufficient), and 5 = nedostatečně (insufficient).