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Peptide amphiphiles were developed in the 1990s. They were first described by the group of Matthew Tirrell in 1995. [5] [6] These first reported PA molecules were composed of two domains: one of lipophilic character and another of hydrophilic properties, which allowed self-assembly into sphere-like supramolecular structures as a result of the association of the lipophilic domains away from the ...
These assemblies have shown promise as agents of drug delivery to cancer cells. Encapsulation can control reactivity. For instance, excited state reactivity of free 1-phenyl-3-tolyl-2-proponanone (abbreviated A-CO-B) yields products A-A, B-B, and AB, which result from decarbonylation followed by random recombination of radicals A• and B•.
With the excellent nature in biodegradation and biocompatibility, supramolecular polymers show great potential in the development of drug delivery, gene transfection and other biomedical applications. [50] Drug delivery: Multiple cellular stimuli could induce responses in supramolecular polymers.
A supramolecular gelator, namely dicyclohexyammonium Boc-glycinate produced gel in nitrobenzene and exhibited self-healing and load-bearing property. [33] This gel was used to create the gel sculptor of "Mother and Child", which is preserved in Kolkata (Indian Association for the Cultivation of Science), India.
A micelle (/ m aɪ ˈ s ɛ l /) or micella (/ m aɪ ˈ s ɛ l ə /) (pl. micelles or micellae, respectively) is an aggregate (or supramolecular assembly) of surfactant amphipathic lipid molecules dispersed in a liquid, forming a colloidal suspension (also known as associated colloidal system). [4]
A Washington, D.C. man has been charged with murder after police say he stabbed his grandmother to death and then texted a photograph of her dead body to other family members last Friday.
The phospholipid amphiphiles are the major structural component of cell membranes. Amphiphiles are the basis for a number of areas of research in chemistry and biochemistry, notably that of lipid polymorphism. Organic compounds containing hydrophilic groups at both ends of the molecule are called bolaamphiphilic.
WASHINGTON (Reuters) - -Alcoholic drinks should carry a label warning consumers about their cancer risks, the U.S. Surgeon General said in an advisory on Friday, noting that their consumption ...