Search results
Results from the WOW.Com Content Network
Substitution reactions in organic chemistry are classified either as electrophilic or nucleophilic depending upon the reagent involved, whether a reactive intermediate involved in the reaction is a carbocation, a carbanion or a free radical, and whether the substrate is aliphatic or aromatic. Detailed understanding of a reaction type helps to ...
The unimolecular nucleophilic substitution (S N 1) reaction is a substitution reaction in organic chemistry. The Hughes-Ingold symbol of the mechanism expresses two properties—"S N " stands for " nucleophilic substitution ", and the "1" says that the rate-determining step is unimolecular .
An example of a substitution reaction taking place by a so-called borderline mechanism as originally studied by Hughes and Ingold [6] is the reaction of 1-phenylethyl chloride with sodium methoxide in methanol. The reaction rate is found to the sum of S N 1 and S N 2 components with 61% (3,5 M, 70 °C) taking place by the latter.
The bimolecular nucleophilic substitution (S N 2) is a type of reaction mechanism that is common in organic chemistry. In the S N 2 reaction, a strong nucleophile forms a new bond to an sp 3-hybridised carbon atom via a backside attack, all while the leaving group detaches from the reaction center in a concerted (i.e. simultaneous) fashion.
In chemistry, S N i (substitution nucleophilic internal) refers to a specific, regio-selective but not often encountered reaction mechanism for nucleophilic aliphatic substitution. The name was introduced by Cowdrey et al. in 1937 to label nucleophilic reactions which occur with retention of configuration, [ 1 ] but later was employed to ...
A single-displacement reaction, also known as single replacement reaction or exchange reaction, is an archaic concept in chemistry. It describes the stoichiometry of some chemical reactions in which one element or ligand is replaced by an atom or group. [1] [2] [3] It can be represented generically as: + +
The Eigen-Wilkins mechanism, named after chemists Manfred Eigen and R. G. Wilkins, [5] is a mechanism and rate law in coordination chemistry governing associative substitution reactions of octahedral complexes. It was discovered for substitution by ammonia of a chromium-(III) hexaaqua complex.
The Williamson ether reaction follows an S N 2 (bimolecular nucleophilic substitution) mechanism. In an S N 2 reaction mechanism there is a backside attack of an electrophile by a nucleophile and it occurs in a concerted mechanism (happens all at once).