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For example, deep white matter hyperintensities are 2.5 to 3 times more likely to occur in bipolar disorder and major depressive disorder than control subjects. [ 3 ] [ 4 ] WMH volume, calculated as a potential diagnostic measure, has been shown to correlate to certain cognitive factors. [ 5 ]
Head CT showing periventricular white matter lesions. Leukoaraiosis is a particular abnormal change in appearance of white matter near the lateral ventricles. It is often seen in aged individuals, but sometimes in young adults. [1] [2] On MRI, leukoaraiosis changes appear as white matter hyperintensities (WMHs) in T2 FLAIR images.
White matter refers to areas of the central nervous system (CNS) that are mainly made up of myelinated axons, also called tracts. [1] Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution of action potentials, acting as a relay and coordinating communication between different brain ...
The normal-exponential-gamma distribution; The normal-inverse Gaussian distribution; The Pearson Type IV distribution (see Pearson distributions) The Quantile-parameterized distributions, which are highly shape-flexible and can be parameterized with data using linear least squares. The skew normal distribution
The simplest case of a normal distribution is known as the standard normal distribution or unit normal distribution. This is a special case when μ = 0 {\textstyle \mu =0} and σ 2 = 1 {\textstyle \sigma ^{2}=1} , and it is described by this probability density function (or density): φ ( z ) = e − z 2 2 2 π . {\displaystyle \varphi (z ...
The gray matter remains normal in all characteristics while the white matter changes texture, becoming soft and gelatinous. Rarefaction of the white matter is seen through light microscopy and the small number of axons and U-fibers that were affected can also be seen. Numerous small cavities in the white matter are also apparent.
In this context, the log-normal distribution has shown a good performance in two main use cases: (1) predicting the proportion of time traffic will exceed a given level (for service level agreement or link capacity estimation) i.e. link dimensioning based on bandwidth provisioning and (2) predicting 95th percentile pricing. [94]
Normal distributions are symmetrical, bell-shaped distributions that are useful in describing real-world data. The standard normal distribution, represented by Z, is the normal distribution having a mean of 0 and a standard deviation of 1.