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[5] [6] [7] It achieves this by inhibiting Ca 2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors. [8] It is the primary drug used for the treatment and prevention of malignant hyperthermia, a rare, life-threatening disorder triggered by general anesthesia or drugs.
Phenazone (INN and BAN; also known as phenazon, antipyrine , antipyrin, [1] or analgesine) is an analgesic (pain reducing), antipyretic (fever reducing) and anti-inflammatory drug. While it predates the term, it is often classified as a nonsteroidal anti-inflammatory drug (NSAID).
A drug combination chart designed for harm reduction by TripSit [1] Polysubstance use or multisubstance use is the use of combinations of psychoactive substances with both legal and illegal substances. This page lists polysubstance combinations that are entheogenic, recreational, or off-label indicated use of pharmaceuticals.
It is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs such as fentanyl. Because of its possible use in the illicit manufacture of fentanyl, the United States Drug Enforcement Administration (DEA) placed NPP under control as a List 1 Chemical in 2007. Both domestic sales and domestic importations are thus subject ...
Phenyltropanes (PTs) are a family of chemical compounds originally derived from structural modification of cocaine.The main feature differentiating phenyltropanes from cocaine is that they lack the ester functionality at the 3-position terminating in the benzene; and thusly the phenyl is attached direct to the tropane skeleton with no further spacer (therefore the name "phenyl"-tropane) that ...
By the 1930s, amphetamine and some of its derivative compounds found use as decongestants in the symptomatic treatment of colds and also occasionally as psychoactive agents. Their effects on the central nervous system are diverse, but can be summarized by three overlapping types of activity: psychoanaleptic , hallucinogenic and empathogenic .
Propyphenazone (known as isopropylantipyrine in Japan) [1] is a derivative of phenazone [2] with similar analgesic and antipyretic effects. Originally patented in 1931, [ 3 ] propyphenazone is marketed as a combination formulation with paracetamol and caffeine for treatment of primary headache disorder .
Imidazo[1,2-a]pyridine—an example of imidazopyridine and a core structure of zolpidem and some compounds described below. An imidazopyridine is a nitrogen containing heterocycle that is also a class of drugs that contain this same chemical substructure.