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Additionally, scientists discovered that participants who were heavy cannabis users also had reduced brain activity in certain areas of the brain, including the dorsolateral prefrontal cortex ...
D’Souza added that cannabis use can have serious impacts on the developing brain because of its effects on the endocannabinoid system, a complex signaling system in the brain that marijuana targets.
The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
A growing body of research and numerous anecdotal reports link cannabis with several health benefits.
It is speculated that this is due to neurotoxic effects of cannabis interfering with critical brain development. [16] [17] Chronic use of cannabis during adolescence, a time when the brain is still developing, is correlated in the long term with lower IQ and cognitive deficits.
3D model of 2-Arachidonoylglycerol, an endocannaboid. The endocannabinoid system (ECS) is a biological system composed of endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the central nervous system (including the brain) and peripheral nervous system.
They are, in effect, released from the postsynaptic cell and act on the presynaptic cell, where the target receptors are densely concentrated on axonal terminals in the zones from which conventional neurotransmitters are released. Activation of cannabinoid receptors temporarily reduces the amount of conventional neurotransmitter released.
Researchers in Italy and the U.K. have found high-potency marijuana can affect the corpus callosum, the nerves that connect the halves of the brain. 'Skunk' marijuana may hinder brain's ability to ...