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Potassium chloride, also known as potassium salt, is used as a medication to treat and prevent low blood potassium. [2] Low blood potassium may occur due to vomiting, diarrhea, or certain medications. [3] The concentrated version should be diluted before use. [2] It is given by slow injection into a vein or by mouth. [4]
Potassium binders are medications that bind potassium ions in the gastrointestinal tract, thereby preventing its intestinal absorption. This category formerly consisted solely of polystyrene sulfonate, a polyanionic resin attached to a cation, administered either orally or by retention enema to patients who are at risk of developing hyperkalaemia (abnormal high serum potassium levels).
Chloride is part of gastric acid (HCl), which plays a role in absorption of electrolytes, activating enzymes, and killing bacteria. The levels of chloride in the blood can help determine if there are underlying metabolic disorders. [20] Generally, chloride has an inverse relationship with bicarbonate, an electrolyte that indicates acid-base ...
The sodium-chloride cotransporter is a protein made up of 1021 amino acids and 12 transmembrane domains. [9] A large number of disease-causing variants throughout the SLC12A3 gene have been reported, including missense, nonsense, frame-shift, splice-site and intronic variants. [10] [11] In 2012, more than 180 mutations of this transporter ...
Side effects may include vomiting, high blood sodium, or high blood potassium. [1] If vomiting occurs, it is recommended that use be paused for 10 minutes and then gradually restarted. [1] The recommended formulation includes sodium chloride, sodium citrate, potassium chloride, and glucose. [1]
Loop diuretics are 90% bonded to proteins and are secreted into the proximal convoluted tubule through organic anion transporter 1 (OAT-1), OAT-2, and ABCC4.Loop diuretics act on the Na +-K +-2Cl − symporter (NKCC2) in the thick ascending limb of the loop of Henle to inhibit sodium, chloride and potassium reabsorption.
Polystyrene sulfonates are a group of medications used to treat high blood potassium. [1] Effects generally take hours to days. [1] They are also used to remove potassium, calcium, and sodium from solutions in technical applications. Common side effects include loss of appetite, gastrointestinal upset, constipation, and low blood calcium. [1]
The product is intended to be used in dogs, primarily as an antiepileptic (to stop seizures). [5] The pink color of the solution is artificial; pure potassium bromide solutions are colorless. The anticonvulsant properties of potassium bromide were first noted by Sir Charles Locock at a meeting of the Royal Medical and Chirurgical Society in 1857