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Neonatal tetanus (trismus nascentium) is a form of generalised tetanus that occurs in newborns. Infants who have not acquired passive immunity from an immunized mother are at risk. It usually occurs through infection of the unhealed umbilical stump, particularly when the stump is cut with a non-sterile instrument.
Neonatal tetanus (trismus nascentium) is a form of generalized tetanus that occurs in newborns, usually those born to mothers who themselves have not been vaccinated. If the mother has been vaccinated against tetanus, the infants acquire passive immunity, and are thus protected. [15]
Tetanus antiserum was developed in 1890, with its protective effects lasting a few weeks. [9] [10] The tetanus toxoid vaccine was developed in 1924, and came into common use for soldiers in World War II. [2] [11] Its use resulted in a 95% decrease in the rate of tetanus. [2] It is on the World Health Organization's List of Essential Medicines. [12]
1 Diseases of neonates and children younger than five years. ... These include pertussis, poliomyelitis, diphtheria, measles, and tetanus.
In infants that weigh under 1500 g, sepsis is the most common cause of death. Three to four percent of infants per 1000 births contract sepsis. The mortality rate from sepsis is near 25%. [36] Infected sepsis in an infant can be identified by culturing the blood and spinal fluid and if suspected, intravenous antibiotics are usually started.
Tetanus is often referred to as lockjaw due to the fact that the bacteria (Clostridium tetani) cause the muscles of the jaw to tighten, which makes the infected person unable to open their mouth. Today in the United States, tetanus is an uncommon disease with an average of only 29 cases reported per year between 1996 and 2009.
In France, children are given DTaP-Hib-HepB-IPV vaccines at 2 months (first dose) and 4 months (second dose) with a booster at 11 months of age. A tetravalent booster for diphtheria, pertussis, tetanus and poliomyelitis is given at 6 years, at 11–13 years, then at 25, 45, 65 years of age, then every 10 years. [50]
In 1900, the smallpox vaccine was the only one administered to children. By the early 1950s, children routinely received three vaccines, for protection against diphtheria, pertussis, tetanus, and smallpox, and as many as five shots by two years of age. [4] Since the mid-1980s, many vaccines have been added to the schedule.