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Its deficiency can cause neurodevelopmental problems which can be partly reversible with early treatment. [27] Only a small subset of dementia cases have been found to be reversible with vitamin B 12 therapy. [28] Tinnitus may be associated with vitamin B 12 deficiency. [29] Vitamin B 12 deficiency may accompany certain eating disorders or ...
Neuropsychiatric symptoms can precede hematological signs and are often the presenting manifestation of the disease. [55] Vitamin B 12 serum levels are used to detect its deficiency, but do not distinguish its causes. Vitamin B 12 levels can be falsely high or low and data for sensitivity and specificity vary widely.
Lack of vitamin B12 can cause megaloblastic anemia—a condition characterized by larger than normal red blood cells in a smaller than normal amount. This causes fatigue, paleness in the skin ...
“A B12 deficiency can cause physical and neurological symptoms, and research is also growing to support that it can also cause psychological issues as well,” says Shapiro. The list of ...
Pernicious anemia is the most common cause of vitamin B 12 deficiency. [17] While it technically refers to anemia caused specifically by autoimmune deficiency of intrinsic factor, it is commonly used to refer to B 12 -deficient anemia as a whole, regardless of cause.
Over time, a deficiency of B12 can cause problems with balance, confusion, depression, poor memory and possibly dementia, and it can even cause permanent damage to the nervous system, Somers says.
[6] [2] [7] Only some archaea and bacteria can synthesize vitamin B 12. [8] Vitamin B 12 deficiency is a widespread condition that is particularly prevalent in populations with low or no consumption of animal foods. [9] Such diets can be due to a variety of reasons, such as low socioeconomic status or personal choice (i.e., veganism ...
As a consequence of the biochemical reactions in which homocysteine is involved, deficiencies of vitamin B 6, folic acid (vitamin B 9), and vitamin B 12 can lead to high homocysteine levels. [2] Other possible causes of hyperhomocysteinemia include genetics, excessive methionine intake, and other diseases.