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Lipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group of pharmaceuticals that are used to lower the level of lipids and lipoproteins, such as cholesterol, in the blood (hyperlipidemia). The American Heart Association recommends the descriptor ...
Pharmacologic (1- to 3-gram/day) niacin doses increase HDL levels by 10–30%, [62] making it the most powerful agent to increase HDL-cholesterol. [63] [64] A randomized clinical trial demonstrated that treatment with niacin can significantly reduce atherosclerosis progression and cardiovascular events. [65]
Medical practitioners prescribe recommended doses up to 2000 mg per day of niacin in either immediate-release or slow-release formats, to lower plasma triglycerides and low-density lipiprotein cholesterol. [25] Vitamin B 5: None: No toxicity known. Vitamin B 6: US UL = 100 mg/day; EU UL = 25 mg/day: See Megavitamin-B 6 syndrome for more ...
For example, Hensrud advised against using niacin, which lowers cholesterol but has side effects, among them flushing. It also can raise liver enzymes when taken in large doses, Hensrud said ...
Salmon. This fatty fish is one of nature’s best sources of omega-3s. A 2023 study published in the Journal of the American Heart Association found that consuming 2 grams of EPA and DHA—the two ...
There are prescription medications like Niaspan and its generic equivalent niacin ER that deliver 500 to 1,000 milligrams of extended-release niacin that are used to treat high blood cholesterol ...
Niacin/simvastatin (trade name Simcor, by Abbott) is a combination drug consisting of an extended release form of the lipid-lowering drug niacin and the statin drug simvastatin. [1] It is used for the treatment of dyslipidemia. It was approved by the FDA on February 15, 2008. [2]
Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a lipid-lowering agent.It reduces triglyceride levels and increases HDL cholesterol. It may have less marked adverse effects than niacin, although it is unclear whether the recommended dose is as effective as standard doses of niacin.
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