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2,4-Dinitrophenol (2,4-DNP or simply DNP) is an organic compound with the formula HOC 6 H 3 (NO 2) 2. It has been used in explosives manufacturing and as a pesticide and herbicide. In humans, DNP causes dose-dependent mitochondrial uncoupling , causing the rapid loss of ATP as heat and leading to uncontrolled hyperthermia —up to 44 °C (111 ...
The substance has killed at least 33 people in the UK. For premium support please call: 800-290-4726 more ways to reach us
2,4-Dinitrophenol (DNP) is a very strong thermogenic drug used for fat loss which produces a dose-dependent increase in body temperature, to the point where it can induce death by hyperthermia. It works as a mitochondrial oxidative phosphorylation uncoupler, disrupting the mitochondrial electron transport chain .
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HU6 is a prodrug of the mitochondrial uncoupler 2,4-dinitrophenol (DNP) that is intended to "minimize the rapid absorption and high peak blood concentrations of DNP to provide a wider therapeutic index and improve safety."
Nicholas Bachynsky (born 1942 or 1943) [1] is a Russian-born American former doctor and convicted fraudster. In the 1980s, he ran a weight loss clinic in Texas where he provided the unlicensed drug 2,4-Dinitrophenol (DNP) to patients under the name "Mitcal"; court filings reported that he had treated 14,000 people with the drug.
The statement was the first by the new government since the outgoing administration earlier this month released a list of 15 drugs that are set to undergo the price negotiation process. At the ...
Oral administration of a liquid. In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body. [1] Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration ...