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Coinfection is the simultaneous infection of a host by multiple pathogen species. In virology, coinfection includes simultaneous infection of a single cell by two or more virus particles. An example is the coinfection of liver cells with hepatitis B virus and hepatitis D virus, which can arise incrementally by initial infection followed by ...
Viral interference is considered the most common outcome of coinfection, or the simultaneous infection of a host by two or more distinct viruses. [5] The primary form of viral interference is known as superinfection exclusion, in which the initial infection stimulates a resistance to subsequent infection by related viruses.
The T4 genome is terminally redundant. Upon DNA replication, long multi-genome length concatemers are formed, perhaps by a rolling circle mechanism of replication. [6] When packaged, the concatemer is cut at unspecific positions of the same length, leading to several genomes that represent circular permutations of the original. [7]
When a large distance separates the source and the target (a small activation site), the redundancy principle explains that this geometrical gap can be compensated by large number. Had nature used less copies than normal, activation would have taken a much longer time, as finding a small target by chance is a rare event and falls into narrow ...
A viral infection does not always cause disease. A viral infection simply involves viral replication in the host, but disease is the damage caused by viral multiplication. [5] An individual who has a viral infection but does not display disease symptoms is known as a carrier. [17] Mechanisms by which viruses cause damage and disease to host cells
Relevant microbes may be viruses, bacteria, or fungi, and they may be spread through breathing, talking, coughing, sneezing, spraying of liquids, toilet flushing or any activities which generate aerosol particles or droplets or generate fomites, such as raising of dust.
The mechanism of infection stems from the conversion of relaxed circular double stranded DNA (rcDNA) into cccDNA, from virus templates, speculated to be performed by the cell's own DNA repair enzymes. This process occurs due to the retrotranscription of a cccDNA transcript into the normal cell's rcDNA genomes.
Transmissibility is the probability of an infection, given a contact between an infected host and a noninfected host. [8] Community transmission means that the source of infection for the spread of an illness is unknown or a link in terms of contacts between patients and other people is missing. It refers to the difficulty in grasping the ...