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What do antidepressants treat? Contrary to what its name suggests, antidepressant medication is prescribed to treat more than clinical depression. The Food and Drug Administration has approved ...
Popular Over-the-Counter Antidepressant Alternatives. So yes, there are big differences between antidepressants and over-the-counter meds. However, some people definitely think they benefit from ...
There are dozens of antidepressants on the market, and they work extremely well for a lot of people. But they have little or no effect for as many as half those who try them.
This delay can explain the reason why antidepressants do not have effect on depression immediately. This can also be the reason why the antidepressant mechanisms can be connected to the increasing neuro impulse flow from 5-HT neurons, where as the concentration of 5-HT increases at the axon terminal before SSRIs start to work properly.
The pharmacology of antidepressants is not entirely clear.. The earliest and probably most widely accepted scientific theory of antidepressant action is the monoamine hypothesis (which can be traced back to the 1950s), which states that depression is due to an imbalance (most often a deficiency) of the monoamine neurotransmitters (namely serotonin, norepinephrine and dopamine). [1]
However, there are differences between TCA related antidepressants and classical TCAs in terms of side effect profiles and withdrawal when compared to SSRIs. [67] There is evidence a prominent side-effect of antidepressants, emotional blunting, is confused with a symptom of depression itself. The cited study, according to Professor Linda Gask was:
The truth is, antidepressants don’t always work — at least, not all antidepressants work for everyone. In fact, it’s not uncommon for people to try multiple antidepressants before finding ...
Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1] They act by antagonizing the α 2 -adrenergic receptor and certain serotonin receptors such as 5-HT 2A and 5-HT 2C , [ 1 ] but also 5-HT 3 , [ 1 ] 5-HT 6 , and/or 5-HT 7 in some cases.
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