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  2. Diagnosis of tuberculosis - Wikipedia

    en.wikipedia.org/wiki/Diagnosis_of_tuberculosis

    A complete medical evaluation for tuberculosis (TB) must include a medical history, a physical examination, a chest X-ray and microbiological examination (of sputum or some other appropriate sample). It may also include a tuberculin skin test, other scans and X-rays, surgical biopsy.

  3. Mantoux test - Wikipedia

    en.wikipedia.org/wiki/Mantoux_test

    The test was first developed and described by the German physician Felix Mendel in 1908. [2] It is named after Charles Mantoux, a French physician who built on the work of Koch and Clemens von Pirquet to create his test in 1907. However, the test was unreliable due to impurities in tuberculin which tended to cause false results. [3]

  4. GeneXpert MTB/RIF - Wikipedia

    en.wikipedia.org/wiki/GeneXpert_MTB/RIF

    In a clinical study conducted the sensitivity of the MTB/RIF test on just 1 sputum sample was 92.2% for culture-positive TB; 98.2% for smear+ and culture-positive cases; and 72.5% for smear-negative, culture-positive cases, with a specificity of 99.2%. Sensitivity and higher specificity were slightly higher when 3 samples were tested. [10]

  5. T-SPOT.TB - Wikipedia

    en.wikipedia.org/wiki/T-SPOT.TB

    T-SPOT.TB counts the number of antimycobacterial effector T cells, white blood cells that produce interferon-gamma, in a sample of blood.This gives an overall measurement of the host immune response against mycobacteria, which can reveal the presence of infection with Mycobacterium tuberculosis, the causative agent of tuberculosis (TB).

  6. Quantiferon - Wikipedia

    en.wikipedia.org/wiki/QuantiFERON

    The Quantiferon-TB Gold test (QFT-G) is a whole-blood test for use as an aid in diagnosing Mycobacterium tuberculosis infection, including latent tuberculosis infection (LTBI) and tuberculosis (TB) disease. [15] This test was approved by the U.S. Food and Drug Administration (FDA) in 2005. Blood samples are mixed with antigens (substances that ...

  7. Tine test - Wikipedia

    en.wikipedia.org/wiki/Tine_test

    The tine test is a multiple-puncture tuberculin skin test used to aid in the medical diagnosis of tuberculosis (TB). The tine test is similar to the Heaf test, although the Mantoux test is usually used instead. There are various forms of the tine tests which usually fall into two categories: the old tine test (OT) and the purified protein ...

  8. Tuberculosis - Wikipedia

    en.wikipedia.org/wiki/Tuberculosis

    A Mantoux tuberculin skin test. The Mantoux tuberculin skin test is often used to screen people at high risk for TB. [100] Those who have been previously immunized with the Bacille Calmette-Guerin vaccine may have a false-positive test result. [107] The test may be falsely negative in those with sarcoidosis, Hodgkin's lymphoma, malnutrition ...

  9. Tuberculosis radiology - Wikipedia

    en.wikipedia.org/wiki/Tuberculosis_radiology

    Persons with these findings, if they have a positive tuberculin skin test reaction, should be considered high-priority candidates for treatment of latent infection regardless of age. Conversely, calcified nodular lesions (calcified granuloma ) pose a very low risk for future progression to active tuberculosis.

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