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  2. ACTH stimulation test - Wikipedia

    en.wikipedia.org/wiki/ACTH_stimulation_test

    The ACTH test (also called the cosyntropin, tetracosactide, or Synacthen test) is a medical test usually requested and interpreted by endocrinologists to assess the functioning of the adrenal glands' stress response by measuring the adrenal response to adrenocorticotropic hormone (ACTH; corticotropin) or another corticotropic agent such as tetracosactide (cosyntropin, tetracosactrin; Synacthen ...

  3. Congenital adrenal hyperplasia due to 21-hydroxylase deficiency

    en.wikipedia.org/wiki/Congenital_adrenal...

    A cosyntropin stimulation test may be needed in mild cases, but usually, the random levels of 17OHP are high enough to confirm the diagnosis. [ 92 ] [ 93 ] [ 94 ] Elevated 17OHP may activate the androgen "backdoor" pathway, that leads to an excess of 5α-dihydrotestosterone and other potent androgens.

  4. Adrenocorticotropic hormone (medication) - Wikipedia

    en.wikipedia.org/wiki/Adrenocorticotropic_hormone...

    Adrenocorticotropic hormone is used as a medication and as diagnostic agent in the ACTH stimulation test. [ 1 ] [ 2 ] : 316, 1165 [ 3 ] : 84, 271 The form that is purified from pig pituitary glands is known as corticotropin [ 1 ] [ 2 ] : 316 is a medication and naturally occurring polypeptide tropic hormone produced and secreted by the anterior ...

  5. Metyrapone - Wikipedia

    en.wikipedia.org/wiki/Metyrapone

    The metyrapone test may aid in verifying the cause of Cushing's syndrome. Most patients with pituitary dysfunction and/or pituitary microadenoma will increase ACTH secretion in response to metyrapone, while most ectopic ACTH-producing tumors will not. Pituitary macroadenomas do not always respond to metyrapone.

  6. Glucocorticoid remediable aldosteronism - Wikipedia

    en.wikipedia.org/wiki/Glucocorticoid_remediable...

    The ACTH stimulation test is sometimes used to stimulate the production of aldosterone along with cortisol to determine if primary or secondary adrenal insufficiency is present. by plasma acidosis. by the stretch receptors located in the atria of the heart. by adrenoglomerulotropin, a lipid factor, obtained from pineal extracts. It selectively ...

  7. TRH stimulation test - Wikipedia

    en.wikipedia.org/wiki/TRH_stimulation_test

    TRH-stimulation testing however continues to be useful for the differential diagnosis of secondary (pituitary disorder) and tertiary (hypothalamic disorder) hypothyroidism. Patients with these conditions appear to have physiologically inactive TSH in their circulation that is recognized by TSH assays to a degree such that they may yield ...

  8. Dexamethasone suppression test - Wikipedia

    en.wikipedia.org/wiki/Dexamethasone_suppression_test

    Low-dose and high-dose variations of the test exist. [4] The test is given at low (usually 1–2 mg) and high (8 mg) doses of dexamethasone, and the levels of cortisol are measured to obtain the results. [5] A low dose of dexamethasone suppresses cortisol in individuals with no pathology in endogenous cortisol production.

  9. Rheobase - Wikipedia

    en.wikipedia.org/wiki/Rheobase

    In such cases, stimulation protocols that utilize the rheobase and assume that spiking rates are proportional to the rheobase will produce nonsense results (e.g. spike rate in response to 2X rheobase will not be greater than at 1.5X rheobase). Bursting cells. Bursting cells will produce multiple spikes once activated. For such cells, it can be ...