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AERD affects an estimated 0.3–0.9% of the general population in the US, including around 7% of all asthmatics, about 14% of adults with severe asthma, and ~5-10% of patients with adult onset asthma. [2] [3] [8] AERD is uncommon among children, with around 6% of patients, predominantly female, reporting disease onset during childhood. [9]
ACO presents with symptoms of both asthma and COPD. [1] ACO presents in adulthood, usually after the age of 40 (after there has been significant tobacco smoke or other toxic fumes exposure), with symptoms of dyspnea (shortness of breath), exercise intolerance, sputum production, cough and episodes of symptomatic worsening known as exacerbations.
Asthma is a common condition and affects over 300 million people around the world. [3] Asthma causes recurring episodes of wheezing, breathlessness, chest tightness, and coughing, particularly at night or in the early morning. [4] Exercise-induced asthma is common in asthmatics, especially after participation in outdoor activities in cold weather.
Patients may watch for symptoms, such as shortness of breath, change in character or amount of mucus, and start self-treatment as discussed with a health care provider. This allows for treatment right away until a doctor can be seen. [5] The symptoms of acute exacerbations are treated using short-acting bronchodilators.
Bronchial hyperresponsiveness is a hallmark of asthma but also occurs frequently in people with chronic obstructive pulmonary disease (COPD). [2] In the Lung Health Study, bronchial hyperresponsiveness was present in approximately two-thirds of patients with non-severe COPD, and this predicted lung function decline independently of other ...
About a third of patients will experience a fever, but fevers due to acute bronchitis rarely rise above 100 °F (37.8 °C) or last longer than a few days. [14] As fever and other systemic symptoms are less common in acute bronchitis than in pneumonia, their presence raises suspicion for the latter, [15] [16] especially high or persistent fevers ...
Acute bronchitis can be defined as acute bacterial or viral infection of the larger airways in healthy patients with no history of recurrent disease. [8] It affects over 40 adults per 1000 each year and consists of transient inflammation of the major bronchi and trachea. [ 9 ]
Chemical exposure, most notably to diacetyl [10] Vaping: On October 17, 2019, the American Journal of Clinical Pathology reported that lung biopsies from patients with vaping-associated pulmonary illness show acute lung injury patterns, including organizing pneumonia. [11] Ionizing radiations [12] [13] Inflammatory diseases. Systemic lupus