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Biorisk Management: Laboratory Biosecurity Guidance. WHO, 2006; Biosafety in Microbiological and Biomedical Laboratories, 5th edition, 2007 ; Clevestig, Peter (28 June 2009). Handbook of Applied Biosecurity for Life Science Laboratories (PDF). Stockholm International Peace Research Institute. ISBN 978-91-85114-61-0. (Website here)
A biosafety level (BSL), or pathogen/protection level, is a set of biocontainment precautions required to isolate dangerous biological agents in an enclosed laboratory facility. The levels of containment range from the lowest biosafety level 1 (BSL-1) to the highest at level 4 (BSL-4).
Biosafety level 4 laboratories are designed for diagnostic work and research on easily respiratory-acquired viruses which can often cause severe and/or fatal disease. What follows is a list of select agents that have specific biocontainment requirements according to US federal law.
Biosafety is the prevention of large-scale loss of biological integrity, focusing both on ecology and human health. [1] These prevention mechanisms include the conduction of regular reviews of biosafety in laboratory settings, as well as strict guidelines to follow. Biosafety is used to protect from harmful incidents.
The American Biological Safety Association (ABSA) was founded in 1984 to promote biosafety as a scientific discipline and to serve the growing needs of biosafety professionals throughout the world. Biosafety concerns the safe handling of biological materials, particularly infectious agents that cause risk to humans working with them.
[1] [4] WHO/Europe also provides tools and training courses in biosafety and biosecurity. [ 5 ] An international Laboratory Biorisk Management Standard developed under the auspices of the European Committee for Standardization , defines biorisk as the combination of the probability of occurrence of harm and the severity of that harm where the ...
Hazardous chemicals present physical and/or health threats to workers in clinical, industrial, and academic laboratories. Laboratory chemicals include cancer-causing agents (carcinogens), toxins (e.g., those affecting the liver, kidney, and nervous system), irritants, corrosives, sensitizers, as well as agents that act on the blood system or damage the lungs, skin, eyes, or mucous membranes.
A biosafety cabinet (BSC)—also called a biological safety cabinet or microbiological safety cabinet—is an enclosed, ventilated laboratory workspace for safely working with materials contaminated with (or potentially contaminated with) pathogens requiring a defined biosafety level.
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