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  2. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    Daily dose tadalafil is available at a dosage of 2.5mg or 5mg tablets. There might be several reasons to go with daily dosages instead of the dosages where you take the medication as needed.

  3. Is It Safe to Take Cialis Daily? - AOL

    www.aol.com/safe-cialis-daily-115900442.html

    Unlike other ED medications, such as Viagra® (sildenafil) and Levitra® (vardenafil), which work for four to five hours per dose, Cialis® (which contains the active ingredient tadalafil) is a ...

  4. Got Headaches from Viagra or Cialis? Here's Why & How to Treat It

    www.aol.com/got-headaches-viagra-cialis-heres...

    Headaches are a common side effect of ED medications such as sildenafil (the active ingredient in Viagra), tadalafil (Cialis) and vardenafil (Levitra), with about 25 percent of men prescribed ...

  5. Tadalafil - Wikipedia

    en.wikipedia.org/wiki/Tadalafil

    Tadalafil is an annulated 2,5-diketopiperazine. [25] It is also a 1,2,3,4-tetrahydro-β-carboline. Tadalafil can be synthesized starting from (D)-tryptophan methyl ester and piperonal via a Pictet–Spengler reaction. This is followed by condensations with chloroacetyl chloride and methylamine to complete the diketopiperazine ring: [26]

  6. Vardenafil - Wikipedia

    en.wikipedia.org/wiki/Vardenafil

    Vardenafil's indications and contraindications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ...

  7. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    Cialis has several common side effects, many of which also happen with other drugs used to treat ED, like sildenafil (generic Viagra®), vardenafil , and avanafil (Stendra®).

  8. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    This allows for a longer therapeutic window and is therefore often a more convenient drug than others with a shorter therapeutic window. Tadalafil is more bioavailable (80%) than sildenafil (40%) and vardenafil (15%) but it has a slow absorption, or about 2 hours compared to 50 minutes of sildenfil. Vardenafil is most known for its potency. [24]

  9. What Is the Safest ED Medication? - AOL

    www.aol.com/safest-ed-medication-105700669.html

    There is no one safest ED drug. Viagra (sildenafil), Cialis (tadalafil), Levitra (vardenafil), Stendra (avanafil) and Caverject (alprostadil) are all FDA-approved for the treatment of ED and safe ...

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