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For approximately 130 miles (210 km), more than half its distance within the state, I-20 is concurrent with I-59 from the Mississippi state line to eastern Birmingham near Birmingham–Shuttlesworth International Airport. Mileage and exits on the concurrency are I-59's, although both highways have the same mileage for the Alabama concurrency.
A portion of the town extends to the northwest into Tuscaloosa County. U.S. Route 11 passes northwest of the town center, leading northeast 31 miles (50 km) to downtown Birmingham and west 26 miles (42 km) to Tuscaloosa. Interstate 59 passes northwest of Woodstock, with the closest access via Exit 97 north of town.
Length (mi) [1] Length (km) Southern or western terminus Northern or eastern terminus Formed Removed Notes I-165: 4.90: 7.89 US 90/Truck US 98/SR 16 at Beauregard & North Water Streets in Mobile: I-65 in Prichard — — I-165 serves as a spur route connecting downtown Mobile with Interstate 65 northwest of Mobile. [2] [3] I-210: 5.10: 8.21 I ...
250.671 mi [1] (403.416 km) Existed: 1926–present: Major junctions; South end: US 11 / US 80 at the Mississippi state line near Cuba: US 80 in Cuba; US 43 / SR 14 in Eutaw; I-20 / I-59 at multiple locations; US 82 in Tuscaloosa; I-459 near McCalla; US 78 / SR 5 in Birmingham; I-65 in Birmingham; I-459 in Birmingham; US 231 at Ashville
U.S. Route 11 passes through the center of the town, leading west 21 miles (34 km) to Tuscaloosa and northeast 36 miles (58 km) to downtown Birmingham. Interstate 59 parallels Route 11 and serves Vance via Exit 89, adjacent to the Mercedes-Benz plant.
U.S. Route 280 (US 280) is a spur of U.S. Highway 80.It currently runs for 392 miles (631 km) from Blitchton, Georgia, at US 80 to Birmingham, Alabama at I-20/I-59.For much of its route, US 280 travels through rural areas and smaller cities in southern Georgia and east central Alabama.
A significant contributor to the city's economy is the Mercedes-Benz U.S. International assembly plant near Vance in Tuscaloosa County, 20 miles (32 km) east of downtown Tuscaloosa, which employs approximately 4,400 (as of 2020). It opened in 1995 and began assembling the R-Class Grand Sport Tourer in 2005.
Interstate 22 (I-22) is a 202.22-mile-long (325.44 km) Interstate Highway in the US states of Mississippi and Alabama, connecting I-269 near Byhalia, Mississippi, to I-65 near Birmingham, Alabama.