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  2. Toxic leukoencephalopathy - Wikipedia

    en.wikipedia.org/wiki/Toxic_leukoencephalopathy

    In contrast to intravenous methotrexate for cancer patients, leukoencephalopathy induced by orally taken methotrexate may be associated with cognitive dysfunction and even death. [citation needed] Oxycodone is the main active ingredient in various oral pain relief medications. [16] High doses of opiates such as oxycodone can lead to ...

  3. Folate deficiency - Wikipedia

    en.wikipedia.org/wiki/Folate_deficiency

    Signs of folate deficiency anemia most of the time are subtle. [4] Anemia (macrocytic, megaloblastic anemia) can be a sign of advanced folate deficiency in adults. [1] Folate deficiency anemia may result in feeling tired, weakness, changes to the color of the skin or hair, open sores on the mouth, shortness of breath, palpitations, lightheadedness, cold hands and feet, headaches, easy bleeding ...

  4. Methotrexate - Wikipedia

    en.wikipedia.org/wiki/Methotrexate

    Methotrexate was originally developed and continues to be used for chemotherapy, either alone or in combination with other agents.It is effective for the treatment of several cancers, including solid tumours of breast, head and neck, lung, bladder, as well as acute lymphocytic leukemias, non-Hodgkin's lymphoma, osteosarcoma, and choriocarcinoma and other trophoblastic neoplasms.

  5. Steroid-induced skin atrophy - Wikipedia

    en.wikipedia.org/wiki/Steroid-induced_skin_atrophy

    higher potency corticosteroids, more frequent application, extended duration of treatment, [3] use of occlusion, infancy/childhood, location [2] Diagnostic method: Visual inspection of skin for visible signs of skin atrophy [1] Prevention: Intermittent maintenance therapy; increasing duration of interval between applications [4] Management

  6. Mercaptopurine - Wikipedia

    en.wikipedia.org/wiki/Mercaptopurine

    [2] [3] For acute lymphocytic leukemia it is generally used with methotrexate. [2] It is taken orally. [2] Common side effects include bone marrow suppression, liver toxicity, vomiting, and loss of appetite. [2] Other serious side effects include an increased risk of future cancer and pancreatitis. [2]

  7. Bone marrow suppression - Wikipedia

    en.wikipedia.org/wiki/Bone_marrow_suppression

    The treatment may mirror that of chemotherapy-induced myelosuppression or may be to change to an alternate drug or to temporarily suspend treatment. Because the bone marrow is the manufacturing center of blood cells, the suppression of bone marrow activity causes a deficiency of blood cells.

  8. Chemotherapy - Wikipedia

    en.wikipedia.org/wiki/Chemotherapy

    Maintenance chemotherapy is a repeated low-dose treatment to prolong remission. [5] [6]: 55–59 Salvage chemotherapy or palliative chemotherapy is given without curative intent, but simply to decrease tumor load and increase life expectancy. For these regimens, in general, a better toxicity profile is expected. [6]: 55–59

  9. Thrombocytopenia - Wikipedia

    en.wikipedia.org/wiki/Thrombocytopenia

    Treatment is guided by the severity and specific cause of the disease. Treatment focuses on eliminating the underlying problem, whether that means discontinuing drugs suspected to cause it or treating underlying sepsis. Diagnosis and treatment of serious thrombocytopenia is usually directed by a hematologist.

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