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Levetiracetam has not been found to be useful for treatment of neuropathic pain, [26] nor for treatment of essential tremors. [27] Levetiracetam has not been found to be useful for treating all developmental disorders within the autism spectrum; [28] [29] studies have only proven to be an effective treatment for partial, myoclonic, or tonic-clonic seizures associated with autism spectrum disorder.
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Seletracetam (UCB 44212) is a pyrrolidone-derived [2] drug of the racetam family that is structurally related to levetiracetam (trade name Keppra). [2] [3] It was under development by UCB Pharmaceuticals as a more potent and effective anticonvulsant drug to replace levetiracetam but its development has been halted.
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[29] [30] In Germany, UCB was unable to demonstrate an additional benefit in 2016, [ 31 ] 2018 [ 32 ] and 2022 [ 33 ] by adding brivaracetam. In Germany, newly approved drugs with new active ingredients have to be evaluated by the Federal Joint Committee (Germany) (Gemeinsamer Bundesausschuss) if the pharmaceutical manufacturer wishes to ...
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