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U.S. Route 421 (US 421) is part of the United States Numbered Highway System that runs from Fort Fisher, North Carolina to Michigan City, Indiana.In the U.S. state of North Carolina, US 421 travels 328 miles (528 km) from its southern terminus at Fort Fisher to the Tennessee state line near the community of Zionville, North Carolina.
In 1952, US 29 was moved onto new bypasses around Lexington and Thomasville, leaving behind US 29A in both cities. ... I-85 north to US 421 south – Durham, Sanford:
In 1934, it was overlapped with US 15 from Durham south to Laurinburg. From there, it went southeast to Rowland and then to the South Carolina border. This extension south replaced NC 22, NC 71, and NC 241. In 1953, US 501 was bypassed around Chapel Hill. In 1956 or 1957, US 501 was bypassed west of Sanford.
US 15/US 501 travel concurrently to Durham. US 1 in Aberdeen. The highways travel concurrently through the city. US 1 south of Sanford. The highways travel concurrently to Sanford. US 421 in Sanford US 64 in Pittsboro I-40 in Durham I-85 / US 70 in Durham. I-85/US 15 travel concurrently to Dutchville Township. US 15/US 70 travel concurrently ...
It joins US 25 at the Blue Grass Army Depot south of Richmond and roughly parallels I-75 towards Lexington. Through Lexington, it is Richmond Road, Main Street and Leestown Road. The segment between Lexington and Frankfort was once designated Kentucky Route 50 (KY 50). US 62 runs briefly with US 421 in this section.
North Carolina Highway 42 (NC 42) is a primary state highway in the U.S. state of North Carolina and a semi-urban traffic artery connecting Asheboro, Sanford, Clayton, Wilson and Ahoskie as well as many small- to medium-sized towns throughout Central and Eastern North Carolina.
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The entire route between Sanford to Apex became a freeway by the mid-1990s. [ 13 ] [ 14 ] [ failed verification ] In 1999, the North Carolina Department of Transportation (NCDOT) submitted a request to the American Association of State Highway and Transportation Officials (AASHTO) to designate 32.36 miles (52.08 km) of US 1 from I-40, in ...