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Somatostatin is secreted by delta cells at several locations in the digestive system, namely the pyloric antrum, the duodenum and the pancreatic islets. [14]Somatostatin released in the pyloric antrum travels via the portal venous system to the heart, then enters the systemic circulation to reach the locations where it will exert its inhibitory effects.
[2] [4] [9] Another topic of interest for beta-cell physiologists is the mechanism of insulin pulsatility which has been well investigated. [ 41 ] [ 42 ] Many genome studies have been completed and are advancing the knowledge of beta-cell function exponentially.
Print/export Download as PDF; Printable version; In other projects ... Somatostatin receptors are receptors for the ligand somatostatin, ...
Print/export Download as PDF; Printable version; In other projects ... Pages in category "Somatostatin inhibitors" The following 8 pages are in this category, out of ...
20607 Ensembl ENSG00000278195 ENSMUSG00000044933 UniProt P32745 P30935 RefSeq (mRNA) NM_001051 NM_001278687 NM_009218 NM_001356961 RefSeq (protein) NP_001042 NP_001265616 NP_033244 NP_001343890 Location (UCSC) Chr 22: 37.2 – 37.21 Mb Chr 15: 78.42 – 78.43 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Shekel Somatostatin receptor type 3 is a protein that in humans is encoded by ...
The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. The encoded protein is a member of the superfamily of somatostatin receptors having seven transmembrane segments, and is expressed in highest levels in jejunum and stomach. [6]
Somatostatin receptor type 5 is a protein that in humans is encoded by the SSTR5 gene. [5] Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner.
Somatostatin family; Motilin family; Substance P. Ghrelin is a peptide hormone released from the stomach and liver and is often referred to as the "hunger hormone" since high levels of it are found in individuals that are fasting. Ghrelin agonistic treatments can be used to treat illnesses such as anorexia and loss of appetites in cancer patients.