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The treatment for galactosemic cataract is no different from general galactosemia treatment. In fact, galactosemic cataract is one of the few symptoms that is actually reversible. Infants should be immediately removed from a galactose diet when symptoms present, and the cataract should disappear and visibility should return to normal. [12]
At some point—usually as you enter middle age—most people develop this eye condition, which is a clouding of the eye’s lens that can get progressively worse and impair your vision. According ...
Galactosemia (British galactosaemia, from Greek γαλακτόζη + αίμα, meaning galactose + blood, accumulation of galactose in blood) is a rare genetic metabolic disorder that affects an individual's ability to metabolize the sugar galactose properly.
The accumulation of galactitol and subsequent osmotic swelling can lead to cataracts which are similar to those seen in galactokinase deficiency. [2] Long-term consequences of continued galactose intake can include developmental delay, developmental verbal dyspraxia, and motor abnormalities. Galactosemic females frequently suffer from ovarian ...
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Cataracts affect nearly 22 million Americans age 40 and older. By age 80, more than half of all Americans have cataracts. Direct medical costs for cataract treatment are estimated at $6.8 billion annually. [72] In the eastern Mediterranean region, cataracts are responsible for over 51% of blindness.
In addition to the common complications of cataract surgery, clear lens extraction may also cause premature posterior vitreous detachment and retinal detachment, [2] particularly in patients with high Myopia. However, modern surgical techniques and advanced lens technology have significantly reduced the likelihood of this and other complications.
The FDA decided to place the study on hold after recently available pre-clinical data showed uncontrollable muscle contractions or convulsions in rabbits. Neumora is working with the FDA to ...