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  2. Asparaginase - Wikipedia

    en.wikipedia.org/wiki/Asparaginase

    Asparaginase is an enzyme that is used as a medication and in food manufacturing. [6] [7] As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL). [6] It is given by injection into a vein, or muscle. [6] A pegylated version is also available. [8] In food manufacturing it is used to ...

  3. Asparagine synthetase - Wikipedia

    en.wikipedia.org/wiki/Asparagine_synthetase

    Escherichia coli derived asparagine synthetase is a dimeric protein with each subunit folding into two distinct domains. [4] The N-terminal region consists of two layers of six-stranded antiparallel β-sheets between which is the active site responsible for the hydrolysis of glutamine. [4]

  4. Calaspargase pegol - Wikipedia

    en.wikipedia.org/wiki/Calaspargase_pegol

    Calaspargase pegol is an engineered protein consisting of the E. coli-derived enzyme L-asparaginase II conjugated with succinimidyl carbonate monomethoxypolyethylene glycol . [6] The L-asparaginase portion hydrolyzes L-asparagine to L-aspartic acid depriving the tumor cell of the L-asparagine it needs for survival. [ 6 ]

  5. Chemotherapy regimen - Wikipedia

    en.wikipedia.org/wiki/Chemotherapy_regimen

    A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy. The majority of drugs used in cancer chemotherapy are cytostatic, many via ...

  6. Pegaspargase - Wikipedia

    en.wikipedia.org/wiki/Pegaspargase

    Pegaspargase is a modified version of the enzyme asparaginase which has undergone PEGylation. [8] [6] It works by breaking down the amino acid asparagine that are circulating in the bloodstream. [6] The circulating asparagine is essential for the cancer cells to enable growth since they can't produce their own, in contrast to normal cells. [9]

  7. Radiation treatment planning - Wikipedia

    en.wikipedia.org/wiki/Radiation_treatment_planning

    Doctor reviewing a radiation treatment plan. In radiotherapy, radiation treatment planning (RTP) is the process in which a team consisting of radiation oncologists, radiation therapist, medical physicists and medical dosimetrists plan the appropriate external beam radiotherapy or internal brachytherapy treatment technique for a patient with cancer.

  8. Hormonal therapy (oncology) - Wikipedia

    en.wikipedia.org/wiki/Hormonal_therapy_(oncology)

    Hormonal therapy is used for several types of cancers derived from hormonally responsive tissues, including the breast, prostate, endometrium, and adrenal cortex. Hormonal therapy may also be used in the treatment of paraneoplastic syndromes or to ameliorate certain cancer- and chemotherapy-associated symptoms, such as anorexia.

  9. Medicare Quality Cancer Care Demonstration Act - Wikipedia

    en.wikipedia.org/wiki/Medicare_Quality_Cancer...

    The Quality Cancer Care Demonstration (QCCD) project was developed by a community of oncologists, with inputs from policy experts, to be a national Medicare demonstration project focused on two key aspects of cancer care: treatment planning and end-of-life care. Treatment planning involves all essential components of establishing the cancer ...