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Guanidine exists protonated, as guanidinium, in solution at physiological pH. Guanidinium chloride (also known as guanidine hydrochloride) has chaotropic properties and is used to denature proteins. Guanidinium chloride is known to denature proteins with a linear relationship between concentration and free energy of unfolding.
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Theraderm is an American manufacturer of clinical-grade skin care products, including anti-aging creams and moisturizers, as well as an acne system under an alternate brand: Reversion. The company was founded in 1996 by board-certified plastic and reconstructive surgeon James Beckman, M.D., who is also a biochemist and adjunct associate ...
The last of these is not pre-formulated, but rather is generated at the time of use by combining a cream containing calcium hydroxide (slaked lime) with an "activating solution" of guanidine carbonate. Another type of "no-lye" relaxer uses ammonium thioglycolate, which is also known as perm salt for its use in permanent waves.
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