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  2. PARP inhibitor - Wikipedia

    en.wikipedia.org/wiki/PARP_inhibitor

    Rucaparib: On December 19, 2016, the US FDA granted accelerated approval for previously treated BRCA-mutant ovarian cancer. [8] In April 2018 it was granted FDA approval. Niraparib: In March 2017 approved by US FDA for epithelial ovarian, fallopian tube, and primary peritoneal cancer. [9] [10] Inhibitor of PARP1 and PARP2. [11]

  3. List of antineoplastic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_antineoplastic_agents

    Small cell lung cancer, ovarian cancer and cervical cancer: Diarrhoea, myelosuppression, interstitial lung disease and allergy. 1.05 Anthracyclines: Daunorubicin: IV: Inhibits DNA and RNA synthesis by intercalating DNA base pairs. Inhibits DNA repair by inhibiting topoisomerase II. Acute leukaemias

  4. Olaparib - Wikipedia

    en.wikipedia.org/wiki/Olaparib

    In December 2014, the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) approved olaparib as monotherapy. [7] [14] [13] [11] [12] The FDA approval is in germline BRCA mutated (gBRCAm) advanced ovarian cancer that has received three or more prior lines of chemotherapy.

  5. US FDA grants full approval to AbbVie's ovarian cancer therapy

    www.aol.com/news/us-fda-grants-full-approval...

    (Reuters) -The U.S. Food and Drug Administration said on Friday it had granted traditional approval for AbbVie's "guided missile" cancer therapy, Elahere, for patients with a type of ovarian ...

  6. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.

  7. List of chemotherapeutic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_chemotherapeutic...

    This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer.This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision.

  8. Topotecan - Wikipedia

    en.wikipedia.org/wiki/Topotecan

    Topotecan, sold under the brand name Hycamtin among others, is a chemotherapeutic agent medication that is a topoisomerase inhibitor. It is a synthetic, water-soluble analog of the natural chemical compound camptothecin. It is used in the form of its hydrochloride salt to treat ovarian cancer, lung cancer and other cancer types.

  9. Niraparib - Wikipedia

    en.wikipedia.org/wiki/Niraparib

    Niraparib, sold under the brand name Zejula, is an anti-cancer medication used for the treatment of epithelial ovarian, fallopian tube, or primary peritoneal cancer. [3] [4] [5] It is taken by mouth. [3] [4] It is a PARP inhibitor.

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