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“Before menopause, the main hormone is estrogen, and after menopause, androgens like testosterone become more prevalent,” Stanhiser says. In that case, can testosterone treat menopause symptoms?
For women, a drop in estrogen can cause weight gain, particularly in the abdomen (aka menopause belly). For men, low testosterone is linked to an increase in fat mass. Men with obesity are more ...
Fat cells have a high amount of aromatase, an enzyme that converts testosterone into estrogen (while estrogen is the primary female sex hormone, men need it too, in small amounts).
Although all preparations of a given type of estrogen may be molecularly identical before their introduction into the human body, estrogens administered orally are modified by the liver before entering the bloodstream and most of it is converted to estrone; estrogen bypassing the digestive tract and liver via the skin is not converted to a new ...
Aromatase excess syndrome (AES or AEXS) is a rarely diagnosed genetic and endocrine syndrome which is characterized by an overexpression of aromatase, the enzyme responsible for the biosynthesis of the estrogen sex hormones from the androgens, in turn resulting in excessive levels of circulating estrogens and, accordingly, symptoms of hyperestrogenism.
[139] [140] [141] The combination of a sufficient dosage of a progestogen with very small doses of an estrogen (e.g., as little as 0.5–1.5 mg/day oral estradiol) is synergistic in terms of antigonadotropic effect and is able to fully suppress gonadal testosterone production, reducing testosterone levels to the female/castrate range.
Testosterone is an essential hormone for both men and women, playing an important role in muscle growth and cognitive function. Low levels of the hormone can lead to changes in mood, cognition and ...
Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
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