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Necrosis (from Ancient Greek νέκρωσις (nékrōsis) ' death ') is a form of cell injury which results in the premature death of cells in living tissue by autolysis. [1] The term "necrosis" came about in the mid-19th century and is commonly attributed to German pathologist Rudolf Virchow , who is often regarded as one of the founders of ...
Avascular necrosis (AVN), also called osteonecrosis or bone infarction, is death of bone tissue due to interruption of the blood supply. [1] Early on, there may be no symptoms. [1] Gradually joint pain may develop, which may limit the person's ability to move. [1] Complications may include collapse of the bone or nearby joint surface. [1]
Overview of signal transduction pathways involved in apoptosis. Cell death is the event of a biological cell ceasing to carry out its functions. This may be the result of the natural process of old cells dying and being replaced by new ones, as in programmed cell death, or may result from factors such as diseases, localized injury, or the death of the organism of which the cells are part.
tissue: Greek ἱστός (histós), web, tissue histology: home(o)-similar Greek ὅμοιος (homoios), like, resembling, similar homeopathy: hom(o)-denotes something as "the same" as another or common Greek ὁμός (homós), the same, common homosexuality, homozygote, homophobic humer(o)-of or pertaining to the shoulder (or [rarely] the ...
The role of cell death is the maintenance of tissue and organ homeostasis, for example, the regular loss of skin cells or a more active role seen in involuting tissues like the thymus. Cells die either by accident or design. In fact there are two mechanisms of cell death; necrosis and apoptosis (apoptosis in invertebrates is called cell ...
Infarction is tissue death due to inadequate blood supply to the affected area. It may be caused by artery blockages , rupture, mechanical compression, or vasoconstriction . [ 1 ] The resulting lesion is referred to as an infarct [ 2 ] [ 3 ] (from the Latin infarctus , "stuffed into").
Myocardial infarction (MI) refers to tissue death of the heart muscle caused by ischemia, the lack of oxygen delivery to myocardial tissue. It is a type of acute coronary syndrome , which describes a sudden or short-term change in symptoms related to blood flow to the heart. [ 22 ]
Ischemia is a vascular disease involving an interruption in the arterial blood supply to a tissue, organ, or extremity that, if untreated, can lead to tissue death. It can be caused by embolism , thrombosis of an atherosclerotic artery, or trauma.