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  2. Assessment of kidney function - Wikipedia

    en.wikipedia.org/wiki/Assessment_of_kidney_function

    Creatinine clearance exceeds GFR due to creatinine secretion, [4] which can be blocked by cimetidine. Both GFR and C Cr may be accurately calculated by comparative measurements of substances in the blood and urine, or estimated by formulas using just a blood test result ( eGFR and eC Cr ) The results of these tests are used to assess the ...

  3. Cystatin C - Wikipedia

    en.wikipedia.org/wiki/Cystatin_C

    The UK's National Institute for Health and Care Excellence (NICE) guideline for the assessment and management of CKD in adults concluded that using serum cystatin C to estimate GFR is more specific for important disease outcomes than use of serum creatinine, and may reduce overdiagnosis in patients with a borderline diagnosis, reducing ...

  4. Glomerular filtration rate - Wikipedia

    en.wikipedia.org/wiki/Glomerular_filtration_rate

    Cystatin C levels are therefore measured not in the urine, but in the bloodstream. Equations have been developed linking estimated GFR to serum cystatin C levels. [16] Most recently, some proposed equations have combined sex, age, adjusted cystatin C and creatinine.

  5. Creatinine - Wikipedia

    en.wikipedia.org/wiki/Creatinine

    Diagnostic serum creatinine studies are used to determine renal function. [4] The reference interval is 0.6–1.3 mg/dL (53–115 μmol/L). [4] It is simple to measure serum creatinine, and it is the most commonly used indicator of renal function. [6]

  6. Basic metabolic panel - Wikipedia

    en.wikipedia.org/wiki/Basic_metabolic_panel

    Outside the United States, blood tests made up of the majority of the same biochemical tests are called urea and electrolytes (U&E or "U and Es"), or urea, electrolytes, creatinine (UEC or EUC or CUE), and are often referred to as 'kidney function tests' as they also include a calculated estimated glomerular filtration rate. The BMP provides ...

  7. Renal clearance ratio - Wikipedia

    en.wikipedia.org/wiki/Renal_clearance_ratio

    C x is the renal plasma clearance of X C in is the renal plasma clearance of inulin . Creatinine is sometimes used instead of inulin as the reference substance; for example, the calcium-creatinine clearance ratio is used in an attempt to distinguish between different causes of a high plasma calcium concentration. [ 3 ]

  8. Andrew S. Levey - Wikipedia

    en.wikipedia.org/wiki/Andrew_S._Levey

    Levey is known for developing the most widely used equations to estimate GFR (renal function) globally.He pioneered work with the MDRD Study Equation, [1] led the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), which pooled measured kidney function CKD data from studies all over the world to develop equations to estimate kidney function from serum creatinine, cystatin C, and ...

  9. Anders Grubb - Wikipedia

    en.wikipedia.org/wiki/Anders_Grubb

    This comparative procedure allowed the definition of a new type of kidney disorder characterized by a greater reduction of renal clearances of larger molecules (e.g. cystatin C, 13,343Da) than of smaller ones (e.g. creatinine, 113Da) and identified by a greater reduction of the cystatin C-based GFR-estimate (eGFR cystatin C) than that based ...

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